Bipolar disorder is associated with high mortality, and people with this disorder on average
may die 10–20 years earlier than the general population. This excess and premature …

Importance Bipolar disorder is associated with premature mortality, but the specific causes
and underlying pathways are unclear. Objective To examine the physical health effects of …

Importance Bipolar disorder affects approximately 8 million adults in the US and
approximately 40 million individuals worldwide. Observations Bipolar disorder is …

Objective: Despite recent evidence that patients with bipolar disorder are at increased risk of
premature mortality resulting from general medical disorders, there has been no systematic …

Background Somatic diseases, including cardiovascular, respiratory, and cancer diseases,
are the main contributors to a shortened life expectancy of 10–20 years in patients with …

Objective Bipolar disorder (BD) is associated with premature mortality. All-cause and
specific mortality risks in this population remain unclear, and more studies are still needed to …

Depression in bipolar disorder (BD) patients presents major clinical challenges. As the
predominant psychopathology even in treated BD, depression is associated not only with …

Bipolar disorder is associated with increased mortality because of complications of
commonly comorbid substance use and stresssensitive medical disorders as well as …

Background Mortality rates, in particular due to suicide, are especially high in bipolar
patients. This nationwide, registry-based study analyses the associations of medication use …

Objectives To compare mortality rates in bipolar disorder with common causes of mortality.
Methods Observational data from the Prechter Longitudinal Study of Bipolar Disorder (PLS …