[HTML][HTML] Progress and roadblocks in the search for brain-based biomarkers of autism and attention-deficit/hyperactivity disorder

LQ Uddin, DR Dajani, W Voorhies, H Bednarz… - Translational …, 2017 - nature.com
Children with neurodevelopmental disorders benefit most from early interventions and
treatments. The development and validation of brain-based biomarkers to aid in objective …

[HTML][HTML] Developing a predictive gene classifier for autism spectrum disorders based upon differential gene expression profiles of phenotypic subgroups

VW Hu, Y Lai - North American journal of medicine & science, 2013 - ncbi.nlm.nih.gov
Autism spectrum disorders (ASD) are neurodevelopmental disorders which are currently
diagnosed solely on the basis of abnormal stereotyped behavior as well as observable …

The Autism Birth Cohort: a paradigm for gene–environment–timing research

C Stoltenberg, S Schjølberg, M Bresnahan… - Molecular …, 2010 - nature.com
The reported prevalence of autism spectrum disorders (ASDs) has increased by 5-to 10-fold
over the past 20 years. Whether ASDs are truly more frequent is controversial; nonetheless …

Ethical dimensions of translational developmental neuroscience research in autism

A Manzini, EJH Jones, T Charman… - Journal of Child …, 2021 - Wiley Online Library
Background Since the 1990s, increasing research has been devoted to the identification of
biomarkers for autism to help attain more objective diagnosis; enable early prediction of …

[HTML][HTML] Clinical genetics evaluation in identifying the etiology of autism spectrum disorders: 2013 guideline revisions

GB Schaefer, NJ Mendelsohn… - Genetics in …, 2013 - Elsevier
The autism spectrum disorders are a collective of conditions that have in common impaired
socialization and communication in association with stereotypic behaviors. The reported …

[HTML][HTML] Identification and validation of biomarkers for autism spectrum disorders

E Loth, W Spooren, LM Ham, MB Isaac… - Nature reviews Drug …, 2016 - nature.com
(DSM5), the core symptoms of ASD comprise deficits in social communication and inter
action, and repetitive and restricted behaviours, which include sensory abnormalities. Novel …

[HTML][HTML] Autism spectrum disorders: an updated guide for genetic counseling

K Griesi-Oliveira, AL Sertié - Einstein (Sao Paulo), 2017 - SciELO Brasil
Autism spectrum disorder is a complex and genetically heterogeneous disorder, which has
hampered the identification of the etiological factors in each patient and, consequently, the …

[HTML][HTML] State of the art of genetic testing for patients with autism: a practical guide for clinicians

BL Kreiman, RG Boles - Seminars in Pediatric Neurology, 2020 - Elsevier
The explosion in knowledge, technology, and clinical capabilities regarding genetics and
genetic testing has expanded greatly in recent years, and these gains have rapidly been …

[HTML][HTML] Predicting autism in infancy

JJ Wolff, J Piven - Journal of the American Academy of Child and …, 2021 - ncbi.nlm.nih.gov
By definition, autism spectrum disorder (ASD) emerges during early childhood. However,
despite longstanding recommendations for earlier identification and intervention, there has …

Metabolism-associated markers and childhood autism rating scales (CARS) as a measure of autism severity

A El-Ansary, G Bjørklund, AM Khemakhem… - Journal of Molecular …, 2018 - Springer
Autism spectrum disorder (ASD) is a neuro-behavioral syndrome with a broad spectrum of
different mechanisms and etiologies that are caused by abnormal brain development. To …