Chronic affective disorders have generated much interest during the past decade due to
increasing recognition of their clinical importance and because of controversy about their …

Cyclothymic disorder is a subtype of bipolar disorder included in the Diagnostic and
Statistical Manual of Mental Disorders since 1980, but largely neglected in research …

Data emerging from both academic centers and from public and private outpatient facilities
indicate that from 20% to 50% of all subjects that seek help for mood, anxiety, impulsive and …

Department of Psychiatry, Harvard Medical School and Psychopharmacology Program,
McLean Division of Massachusetts General Hospital, Boston, Mass., and b International …

The authors identified 46 cyclothymic probands from a random pool of 500 psychiatric
outpatients and prospectively followed them over a 2-3 year period. They used 50 bipolar …

BACKGROUND: Four subtypes of bipolar disorder (BP)–bipolar I, bipolar II, cyclothymia and
bipolar not otherwise specified (NOS)–are defined in DSM-IV-TR. Though the diagnostic …

Background: Contrary to DSM-5 definition based on recurrence of low grade hypomanic and
depressive symptoms, cyclothymia is better defined in a neurodevelopmental perspective as …

Discusses the relevance of E. Hecher's description of cyclothymia as cyclical mood disorder
to the modern concept of bipolar II. His clinical description and recommendations are …

OBJECTIVE: While there is an increasing recognition of the role of subthreshold
symptomatology in bipolar disorder, little attention has been dedicated to its only formally …

Kraepelin had a modern vision of affective illness. He hypothesized that affective
recurrences arose from enduring dispositions of depressive, cyclothymic, irritable, or …