MT1-MMP in breast cancer: induction of VEGF-C correlates with metastasis and poor prognosis
G Yao, P He, L Chen, X Hu, F Gu, C Ye - Cancer Cell International, 2013 - Springer
Background Recent evidence suggests that vascular endothelial growth factor-C (VEGF-C)-
dependent tumour production promotes lymphangiogenesis, while membrane-type matrix 1 …
dependent tumour production promotes lymphangiogenesis, while membrane-type matrix 1 …
MT1-MMP up-regulates VEGF expression in human breast carcinoma MCF-7 cells and induces tumor angiogenesis
YP Deng, W Li, YL Li, H Xu, SS Liang… - Zhonghua zhong liu za …, 2009 - europepmc.org
Objective To study the function of MT1-MMP in tumor angiogenesis and elucidate the
possible way of action that MT1-MMP contributes to angiogenesis. Methods MT1-MMP was …
possible way of action that MT1-MMP contributes to angiogenesis. Methods MT1-MMP was …
Cancer cell–associated MT1-MMP promotes blood vessel invasion and distant metastasis in triple-negative mammary tumors
JY Perentes, ND Kirkpatrick, S Nagano, EY Smith… - Cancer research, 2011 - AACR
Functional roles for the cancer cell–associated membrane type I matrix metalloproteinase
(MT1-MMP) during early steps of the metastatic cascade in primary tumors remain …
(MT1-MMP) during early steps of the metastatic cascade in primary tumors remain …
[HTML][HTML] MT2-MMP expression associates with tumor progression and angiogenesis in human lung cancer
L Chen, Q Zhou, B Xu, J Liu, L Shi, D Zhu… - … Journal of Clinical …, 2014 - ncbi.nlm.nih.gov
Matrix metalloproteinases (MMPs) are a family of important proteolytic enzymes that play an
important role in the remodeling of the tumor microenvironment and associate with …
important role in the remodeling of the tumor microenvironment and associate with …
Less is more: low expression of MT1-MMP is optimal to promote migration and tumourigenesis of breast cancer cells
MA Cepeda, JJH Pelling, CL Evered, KC Williams… - Molecular cancer, 2016 - Springer
Abstract Background Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) is a
multifunctional protease implicated in metastatic progression ostensibly due to its ability to …
multifunctional protease implicated in metastatic progression ostensibly due to its ability to …
Decreased MT1-MMP in gastric cancer suppressed cell migration and invasion via regulating MMPs and EMT
W Li, S Li, L Deng, S Yang, M Li, S Long, S Chen, F Lin… - Tumor Biology, 2015 - Springer
Membrane type 1-matrix metalloproteinase (MT1-MMP) has been identified to play a
significant role in several types of cancers, but little is known about the significance of MT1 …
significant role in several types of cancers, but little is known about the significance of MT1 …
The role of MT2-MMP in cancer progression
E Ito, I Yana, C Fujita, A Irifune, M Takeda… - Biochemical and …, 2010 - Elsevier
The role of MT2-MMP in cancer progression remains to be elucidated in spite of many
reports on MT1-MMP. Using a human fibrosarcoma cell, HT1080 and a human gastric …
reports on MT1-MMP. Using a human fibrosarcoma cell, HT1080 and a human gastric …
[HTML][HTML] Increased MT2-MMP expression in gastric cancer patients is associated with poor prognosis
X Xu, L Chen, B Xu, Q Xie, M Sun, X Deng… - … Journal of Clinical …, 2015 - ncbi.nlm.nih.gov
Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that contribute to
tumorigenesis and metastasis due to their ability to degrade the extracellular matrix (ECM) …
tumorigenesis and metastasis due to their ability to degrade the extracellular matrix (ECM) …
[HTML][HTML] MT1‑MMP promotes the proliferation and invasion of gastric carcinoma cells via regulating vimentin and E‑cadherin
B Li, G Lou, J Zhou - Molecular Medicine Reports, 2019 - spandidos-publications.com
The present study aimed to explore the possible effects of membrane‑type 1 matrix
metalloproteinase (MT1‑MMP) on gastric carcinoma cells proliferation and invasion …
metalloproteinase (MT1‑MMP) on gastric carcinoma cells proliferation and invasion …
Overexpression of MT1-MMP is insufficient to increase experimental liver metastasis of human colon cancer cells
H Yamamoto, S Noura, J Okami… - International …, 2008 - spandidos-publications.com
The expression and activation of matrix metalloproteinases (MMPs) by tumor cells is
correlated with invasive and metastatic potential. The purpose of this study was to examine …
correlated with invasive and metastatic potential. The purpose of this study was to examine …
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