Altered muscarinic and nicotinic receptor densities in cortical and subcortical brain regions in Parkinson's disease
KW Lange, FR Wells, P Jenner… - Journal of …, 1993 - Wiley Online Library
Muscarinic and nicotinic cholinergic receptors and choline acetyltransferase activity were
studied in postmortem brain tissue from patients with histopathologically confirmed …
studied in postmortem brain tissue from patients with histopathologically confirmed …
Brain muscarinic receptor subtypes are differently affected in Alzheimer's disease and Parkinson's disease
JO Rinne, P Lo, UK Rinne - Brain research, 1989 - Elsevier
The muscarinic receptor subtypes determined by displacing [3 H] quinuclidinyl benzylate by
carbachol showed distinct profiles in Alzheimer's disease (AD) and in Parkinson's disease …
carbachol showed distinct profiles in Alzheimer's disease (AD) and in Parkinson's disease …
The cholinergic system in Alzheimer disease
E Giacobini - Progress in brain research, 1990 - Elsevier
Publisher Summary This chapter describes the cholinergic system in Alzheimer disease
(AD). Choline acetyltransferase (ChAT), the synthetic enzyme for acetylcholine (ACh), is …
(AD). Choline acetyltransferase (ChAT), the synthetic enzyme for acetylcholine (ACh), is …
Human nicotinic receptors—their role in aging and dementia
A Nordberg - Neurochemistry international, 1994 - Elsevier
Multiple nicotinic receptors seem to exist in brain as revealed by neurophysiological,
neurochemical, molecular and immunological studies. The mechanisms for their …
neurochemical, molecular and immunological studies. The mechanisms for their …
[引用][C] Cholinergic treatments for Alzheimer's disease
F ROBERTS, S LAZARENO - Biochemical Society Transactions, 1989 - portlandpress.com
FlONA ROBERTS and SEBASTIAN LAZARENO There is a correlation between the reduced
choline acctyl-Depcrrtmetif of Neirrophurmacolo&y, Gluxo Groirp lieserrrch, transferase …
choline acctyl-Depcrrtmetif of Neirrophurmacolo&y, Gluxo Groirp lieserrrch, transferase …
Nicotinic cholinoceptive neurons of the frontal cortex are reduced in Alzheimer's disease
E Giacobini, RG Struble, K Zilles, A Maelicke - Neurobiology of aging, 1991 - Elsevier
The cellular distribution of nicotinic acetylcholine receptors was studied in the frontal cortex
(area 10) of 1) Alzheimer patients and compared to 2) age-matched and 3) middle-aged …
(area 10) of 1) Alzheimer patients and compared to 2) age-matched and 3) middle-aged …
Aging and brain cholinergic muscarinic receptor subtypes: an autoradiographic study in the rat
Cholinergic M1 and M2 muscarinic receptors in aged and young rat brains were studied by
quantitative autoradiography of tritiated QNB in the presence of pirenzepine or carbachol. A …
quantitative autoradiography of tritiated QNB in the presence of pirenzepine or carbachol. A …
Muscarinic receptors and novel strategies for the treatment of age-related brain disorders
FJ Ehlert, WR Roeske, HI Yamamura - Life sciences, 1994 - Elsevier
The muscarinic class of acetylcholine receptors is widely distributed throughout the body
and mediates numerous vital functions in both the brain and autonomic nervous system …
and mediates numerous vital functions in both the brain and autonomic nervous system …
Aging and rat brain muscarinic receptors as measured by quinuclidinyl benzilate binding
AM Morin, CG Wasterlain - Neurochemical Research, 1980 - Springer
Measurement of cholinergic muscarinic receptor binding in various rat brain areas using the
ligand [3 H] quinuclidinyl benzilate indicates that receptor binding is decreased in striatum …
ligand [3 H] quinuclidinyl benzilate indicates that receptor binding is decreased in striatum …