Background Antidepressants are frequently used in older patients with depression, but little
is known about the comparative safety of individual agents. The objective of the study was to …

Objective: The authors investigated the clinical outcomes of commonly used antidepressants
among older adults who initiated first-time antidepressants for depression by analyzing the 1 …

Background: Antidepressant treatment may increase the risk of death. The association
between antidepressants and mortality has been evaluated in community-dwelling older …

In this commentary, we address current clinical practice of long-term antidepressant use in
older adults with depression, and recommend improvements. Compared with younger …

Background Antidepressants are among the most commonly prescribed drugs in primary
care in England and their use is increasing. This is largely due to longer durations of …

Background The choice of antidepressants for initial pharmacological treatment of
depression in older adults and associated patients' characteristics are understudied. We …

Background There is little real-world evidence about effectiveness of different
antidepressants on geriatric depression. Methods We used population-based claims data in …

Aims: To study the impact of the use of antidepressants on dementia in German patients with
depression treated in general (GPs) or psychiatric practices (PPs). Methods: Patients with a …

Background Antidepressants are one of the most commonly prescribed medications in
young and middle-aged adults, but there is relatively little information on their safety across …

Background Depression is one of the leading causes of the global burden of disease, and it
has particularly negative consequences for elderly patients. Antidepressants are the most …