Ferroptosis is a newly discovered form of iron-dependent cell death, which is different from
other death forms. The main characteristics of ferroptosis are:(1) Amino acid metabolism.(2) …

As a regulatory cell death mode defined in recent years, Ferroptosis is mainly characterized
by increased intracellular free iron and the accumulation of lipid peroxides. Ferroptosis is …

The treatment of cancer mainly involves surgical excision supplemented by radiotherapy
and chemotherapy. Chemotherapy drugs act by interfering with tumor growth and inducing …

Currently, mechanisms and therapeutic approaches have been thoroughly studied in
various prevalent malignant tumors, such as breast and lung cancer. However, there is …

Compared with the traditional forms of cell death—apoptosis, necrosis and autophagy,
ferroptosis is a novel form of iron-dependent programmed cell death forms which is different …

Ferroptosis is a novel type of programmed cell death, characterized by a dysregulated iron
metabolism and accumulation of lipid peroxides. It features the alteration of mitochondria …

At present, more than one cell death pathways have been found, one of which is ferroptosis.
Ferroptosis was discovered in 2012 and described as an iron-dependent and lipid …

Ferroptosis is a recently defined, nonapoptotic, regulated cell death (RCD) process that
comprises abnormal metabolism of cellular lipid oxides catalysed by iron ions or iron …

Significance: The significance of ferroptosis in cancer therapeutics has now been unveiled.
Specific ferroptosis inducers are expected as a promising strategy for cancer treatment …

Ferroptosis is an iron-dependent cell death process characterized by excessive
accumulation of reactive oxygen species and lipid peroxidation. The elucidation of …