Differential effects of scopolamine and mecamylamine on working and reference memory in the rat

PM Moran - Pharmacology Biochemistry and Behavior, 1993 - Elsevier
The effects of the muscarinic antagonist scopolamine (0.1–0.6 mg/kg, IP) and the nicotinic
antagonist mecamylamine (1–10 mg/kg) were compared in T-maze alternation and …

Interactions between scopolamine and muscarinic cholinergic agonists or cholinesterase inhibitors on spatial alternation performance in rats.

HE Shannon, KG Bemis, JC Hendrix, JS Ward - Journal of Pharmacology …, 1990 - ASPET
The effects on working memory of the muscarinic cholinergic agonists oxotremorine,
arecoline, RS86 and pilocarpine, and the cholinesterase inhibitors physostigmine and …

Differential effects of scopolamine on working and reference memory depend upon level of training

RG Lydon, S Nakajima - Pharmacology Biochemistry and Behavior, 1992 - Elsevier
Controversy exists whether the cholinergic system in the brain is involved in working
memory (WM) selectively or in both WM and reference memory (RM). Rats were trained to …

Attenuation in rats of impairments of memory by scopolamine, a muscarinic receptor antagonist, by mecamylamine, a nicotinic receptor antagonist

LA Newman, PE Gold - Psychopharmacology, 2016 - Springer
Rationale Scopolamine, a muscarinic antagonist, impairs learning and memory for many
tasks, supporting an important role for the cholinergic system in these cognitive functions …

Effect of huperzine A, a novel acetylcholinesterase inhibitor, on radial maze performance in rats

ZQ Xiong, XC Tang - Pharmacology Biochemistry and Behavior, 1995 - Elsevier
Rats were trained to run in a spatial, radial arm maze using a procedure to determine two
memory functions, working and reference memory. The muscarinic antagonist, not the …

The effects of novel cholinesterase inhibitors and selective muscarinic receptor agonists in tests of reference and working memory

GR Dawson, SD Iversen - Behavioural brain research, 1993 - Elsevier
In recent years muscarinic receptor agonists and cholinesterase inhibitors have been
developed for the treatment of Alzheimer's disease. We have evaluated examples from both …

Concurrent blockade of β-adrenergic and muscarinic receptors disrupts working memory but not reference memory in rats

M Kobayashi, M Ohno, T Yamamoto, S Watanabe - Physiology & behavior, 1995 - Elsevier
In order to clarify the interactions between monoaminergic and cholinergic systems in
working and reference memory functions, the effects of administration of the α, β-adrenergic …

Mecamylamine blocks enhancement of reference memory but not working memory produced by post-training injection of nicotine in rats tested on the radial arm maze

RW Brown, KS Beale, GDJ Frye - Behavioural brain research, 2002 - Elsevier
The focus of this study was to analyze whether the psychostimulant nicotine would enhance
reference and working memory consolidation in rats tested on the 8-arm radial arm maze …

Antagonism of scopolamine-induced memory impairments in rats by the muscarinic agonist RU 35 926 (CI-979)

M M'harzi, AM Palou, C Oberlander… - … Biochemistry and Behavior, 1995 - Elsevier
The promnesic effects of RU 35 926 (CI-979), a muscarinic receptor agonist, were evaluated
on memory impairments induced by the muscarinic antagonist scopolamine, using a radial …

Evaluation of muscarinic and nicotinic receptor antagonists on attention and working memory

JA McQuail, JA Burk - Pharmacology Biochemistry and Behavior, 2006 - Elsevier
Cholinergic receptor antagonists are commonly used to model attentional and mnemonic
impairments associated with neuropsychiatric disorders such as Alzheimer's disease …