Background Cutaneous exposure to food allergens predisposes to food allergy, which is
commonly associated with atopic dermatitis (AD). Levels of the epithelial cytokine IL-33 are …

Atopic dermatitis (AD) often precedes asthma and food allergy, indicating that epicutaneous
sensitization to allergens may be important in the induction of allergic responses at other …

Background Atopic dermatitis (AD) is characterized by a skin barrier defect aggravated by
mechanical injury inflicted by scratching, a TH 2 cell–dominated immune response, and …

Interleukin-33 (IL-33) appears to play a crucial role in the expression of allergic diseases,
but its cellular source and regulatory mechanisms remain to be fully elucidated. Mast cells …

Abstract Interleukin-33 (IL-33) is a member of the interleukin-1 (IL-1) cytokine family. It is
preferentially and constitutively expressed in different structural cells such as epithelial cells …

In the acute phase of atopic dermatitis (AD), T-helper type 2 (Th2) cytokines characterize the
inflammatory response in the skin. IL-33 is a new tissue-derived cytokine, which is mainly …

Anaphylactic shock is characterized by elevated immunoglobulin-E (IgE) antibodies that
signal via the high affinity Fcε receptor (FcεRI) to release inflammatory mediators. Here we …

ABSTRACT Interleukin-33 (IL-33), a member of the IL-1 cytokine family, is preferentially and
constitutively expressed in epithelial cells, and it is especially localized in the cells' nucleus …

Background IL-33 is a recently characterized IL-1 family cytokine and found to be expressed
in inflammatory diseases, including severe asthma and inflammatory bowl disease …

Cutaneous sensitization with a food antigen before its consumption elicits the development
of food allergy. Here, we report the site-and stage-dependent roles of basophils and …