Rapid effect of nicotine intake on neuroplasticity in non-smoking humans

J Grundey, N Thirugnanasambandam… - Frontiers in …, 2012 - frontiersin.org
In various studies nicotine has shown to alter cognitive functions in non-smoking subjects.
The physiological basis for these effects might be nicotine-generated modulation of cortical …

Neuroplasticity in cigarette smokers is altered under withdrawal and partially restituted by nicotine exposition

J Grundey, N Thirugnanasambandam… - Journal of …, 2012 - Soc Neuroscience
Nicotine improves cognitive functions by modulating neuroplasticity and cortical excitability
in nonsmoking subjects. As shown recently, the positive effect of nicotine on cognition might …

Nicotinergic impact on focal and non-focal neuroplasticity induced by non-invasive brain stimulation in non-smoking humans

N Thirugnanasambandam, J Grundey… - …, 2011 - nature.com
Nicotine improves cognitive performance and modulates neuroplasticity in brain networks.
The neurophysiological mechanisms underlying nicotine-induced behavioral changes have …

Compromised neuroplasticity in cigarette smokers under nicotine withdrawal is restituted by the nicotinic α4β2-receptor partial agonist varenicline

G Batsikadze, W Paulus, A Hasan, J Grundey… - Scientific reports, 2017 - nature.com
Nicotine modulates neuroplasticity and improves cognitive functions in animals and
humans. In the brain of smoking individuals, calcium-dependent plasticity induced by non …

Nicotine modulates human brain plasticity via calciumdependent mechanisms

J Grundey, J Barlay, G Batsikadze… - The Journal of …, 2018 - Wiley Online Library
Key points Nicotine (NIC) modulates cognition and memory function by targeting the
nicotinic ACh receptor and releasing different transmitter systems postsynaptically. With both …

Mechanisms of nicotinic modulation of glutamatergic neuroplasticity in humans

MDMV Lugon, G Batsikadze, S Fresnoza… - Cerebral …, 2017 - academic.oup.com
The impact of nicotine (NIC) on plasticity is thought to be primarily determined via calcium
channel properties of nicotinic receptor subtypes, and glutamatergic plasticity is likewise …

Effect of the Nicotinic α4β2-receptor Partial Agonist Varenicline on Non-invasive Brain Stimulation-Induced Neuroplasticity in the Human Motor Cortex

G Batsikadze, W Paulus, J Grundey, MF Kuo… - Cerebral …, 2015 - academic.oup.com
Nicotine alters cognitive functions in animals and humans most likely by modification of
brain plasticity. In the human brain, it alters plasticity induced by transcranial direct current …

Nicotine self-administration impairs hippocampal plasticity

DN Abrous, W Adriani, MF Montaron… - Journal of …, 2002 - Soc Neuroscience
Nicotine, the neuroactive compound responsible for tobacco addiction, is primarily believed
to have beneficial effects on the adult brain. However, in heavy smokers, abstinence from …

Nicotineinduced neuroplasticity in striatum is subregionspecific and reversed by motor training on the rotarod

V Licheri, D Eckernäs, F Bergquist, M Ericson… - Addiction …, 2020 - Wiley Online Library
Nicotine is recognized as one of the most addictive drugs, which in part could be attributed
to progressive neuroadaptations and rewiring of dorsal striatal circuits. Since motorskill …

Diverging effects of nicotine on motor learning performance: improvement in deprived smokers and attenuation in non-smokers

J Grundey, R Amu, G Batsikadze, W Paulus… - Addictive Behaviors, 2017 - Elsevier
Nicotine modulates cognition and neuroplasticity in smokers and non-smokers. A possible
mechanism for its effect on learning and memory performance is its impact on long-term …