This article will touch on theories, scientific research and conjecture about the evolutionary
genetics of the brain function and the impact of genetic variants called polymorphisms on …

The hypothesis issued by modern medicine states that many diseases known to humans are
genetically determined, influenced or not by environmental factors, which is applicable to …

Drug dependence is a chronic, relapsing disorder in which compulsive drug-seeking and
drug-taking behaviours persist despite serious negative consequences. Addictive …

Currently, about 246 million people around the world have used an illicit drug. The reasons
for this use are multiple: eg to augment the sensation of pleasure or to reduce the withdrawal …

Dopamine plays a key role in reward behavior, yet the association of drug dependence as a
chronic, relapsing disorder with the genes encoding the various dopaminergic receptor …

At the end of their report on the successful selective breeding of rat strains with either high or
low susceptibilities to morphine addiction, Nichols and Hsiao (1967) conjecture that …

The term psychogenomics is used here to describe the process of applying the powerful
tools of genomics and proteomics to achieve a better understanding of the biological …

Cocaine addiction is a major health and social problem for which there are presently no
effective pharmacotherapies. Many of the most promising medications target dopamine …

Having entered the genomics era with confidence in the future of medicine, including
psychiatry, identifying the role of DNA and polymorphic associations with brain reward …

Addictions are common psychiatric disorders that exert high cost to the individual and to
society. Addictions are a result of the interplay of multiple genetic and environmental factors …