[HTML][HTML] Characterization of the dimerization interface of membrane type 4 (MT4)-matrix metalloproteinase

A Sohail, M Marco, H Zhao, Q Shi, S Merriman… - Journal of Biological …, 2011 - ASBMB
MT4-MMP (MMP17) belongs to a unique subset of membrane type-matrix
metalloproteinases that are anchored to the cell surface via a glycosylphosphatidylinositol …

[HTML][HTML] Identification and role of the homodimerization interface of the glycosylphosphatidylinositol-anchored membrane type 6 matrix metalloproteinase (MMP25)

H Zhao, A Sohail, Q Sun, Q Shi, S Kim… - Journal of Biological …, 2008 - ASBMB
The membrane type (MT) 6 matrix metalloproteinase (MMP)(MMP25) is a
glycosylphosphatidylinositol-anchored matrix metalloproteinase (MMP) that is highly …

[HTML][HTML] Glycosylation broadens the substrate profile of membrane type 1 matrix metalloproteinase

YI Wu, HG Munshi, R Sen, SJ Snipas… - Journal of Biological …, 2004 - ASBMB
Membrane type 1 matrix metalloproteinase (MT1-MMP) is a collagenolytic enzyme that has
been implicated in normal development and in pathological processes such as cancer …

[HTML][HTML] The cytoplasmic tail dileucine motif LL572 determines the glycosylation pattern of membrane-type 1 matrix metalloproteinase

T Ludwig, SM Theissen, MJ Morton… - Journal of Biological …, 2008 - ASBMB
Membrane-type 1 matrix metalloproteinase (MT1-MMP; MMP-14) drives fundamental
physiological and pathological processes, due to its ability to process a broad spectrum of …

[HTML][HTML] The inactive 44-kDa processed form of membrane type 1 matrix metalloproteinase (MT1-MMP) enhances proteolytic activity via regulation of endocytosis of …

JA Cho, P Osenkowski, H Zhao, S Kim, M Toth… - Journal of Biological …, 2008 - ASBMB
Membrane type 1 (MT1) matrix metalloproteinase (MMP-14) is a membrane-tethered MMP
considered to be a major mediator of pericellular proteolysis. MT1-MMP is regulated by a …

[HTML][HTML] Biochemical characterization of the cellular glycosylphosphatidylinositol-linked membrane type-6 matrix metalloproteinase

IA Radichev, AG Remacle, SA Shiryaev… - Journal of Biological …, 2010 - ASBMB
Ubiquitously expressed membrane type-1 matrix metalloproteinase (MT1-MMP), an
archetype member of the MMP family, binds tissue inhibitor of metalloproteinases-2 (TIMP …

Cleavage at the stem region releases an active ectodomain of the membrane type 1 matrix metalloproteinase

M Toth, P Osenkowski, D Hesek, S Brown… - Biochemical …, 2005 - portlandpress.com
MT1-MMP (membrane type 1 matrix metalloproteinase) is a membrane-anchored MMP that
can be shed to the extracellular milieu. In the present study we report the primary structure …

[HTML][HTML] A unique substrate binding mode discriminates membrane type-1 matrix metalloproteinase from other matrix metalloproteinases

SJ Kridel, H Sawai, BI Ratnikov, EI Chen, W Li… - Journal of Biological …, 2002 - ASBMB
In our study, we characterized the substrate recognition properties of membrane type-1
matrix metalloproteinase (MT1-MMP; also known as MMP-14), a key enzyme in tumor cell …

[HTML][HTML] Membrane type 4 matrix metalloproteinase (MT4-MMP, MMP-17) is a glycosylphosphatidylinositol-anchored proteinase

Y Itoh, M Kajita, H Kinoh, H Mori, A Okada… - Journal of Biological …, 1999 - ASBMB
Among the five membrane-type matrix metalloproteinases (MT-MMPs), MT1-, MT2-, MT3-,
and MT5-MMPs have about a 20-amino acid cytoplasmic tail following the transmembrane …

[HTML][HTML] Regulation of membrane-type-1 matrix metalloproteinase activity by its cytoplasmic domain

K Lehti, H Valtanen, S Wickström, J Lohi… - Journal of Biological …, 2000 - ASBMB
Membrane-type-1 matrix metalloproteinase (MT1-MMP) has transmembrane and
cytoplasmic domains, which target it to invasive fronts. We analyzed the role of the …