Variation in the CACNB2 gene is associated with functional connectivity of the Hippocampus in bipolar disorder

F Liu, X Gong, X Yao, L Cui, Z Yin, C Li, Y Tang… - BMC psychiatry, 2019 - Springer
Background Calcium voltage-gated channel auxiliary subunit β2 is a protein that, in humans,
is encoded by the CACNB2 gene. The β2 subunit is an auxiliary protein of voltage-gated …

CACNA1C rs1006737 genotype and bipolar disorder: Focus on intermediate phenotypes and cardiovascular comorbidity

X Ou, DE Crane, BJ MacIntosh, LT Young… - Neuroscience & …, 2015 - Elsevier
Recently, multiple genome-wide association studies have identified a genetic polymorphism
(CACNA1C rs1006737) that appears to confer susceptibility for BD. This article aims to …

The impact of a CACNA1C gene polymorphism on learning and hippocampal formation in healthy individuals: a diffusion tensor imaging study

B Dietsche, H Backes, D Laneri, T Weikert, SH Witt… - Neuroimage, 2014 - Elsevier
Background Genome-wide association studies have identified the CACNA1C single
nucleotide polymorphism (SNP) rs1006737 as one of the most consistent genetic findings as …

The association of genetic variation in CACNA1C with structure and function of a frontotemporal system

F Wang, AM McIntosh, Y He, J Gelernter… - Bipolar …, 2011 - Wiley Online Library
Wang F, McIntosh AM, He Y, Gelernter J, Blumberg HP. The association of genetic variation
in CACNA1C with structure and function of a frontotemporal system. Bipolar Disord 2011 …

Further evidence for genetic association of CACNA1C and schizophrenia: new risk loci in a Han Chinese population and a meta-analysis

F Zheng, Y Zhang, W Xie, W Li, C Jin, W Mi… - Schizophrenia …, 2014 - Elsevier
Abstract CACNA1C (12p13. 3) has been implicated as a susceptibility gene for
schizophrenia by several replicated genome wide association studies. While these results …

The impact of CACNA1C gene, and its epistasis with ZNF804A, on white matter microstructure in health, schizophrenia and bipolar disorder1

E Mallas, F Carletti, CA Chaddock… - Genes, Brain and …, 2017 - Wiley Online Library
Genomewide studies have identified allele A (adenine) of single nucleotide polymorphism
(SNP) rs1006737 of the calciumchannel CACNA1C gene as a risk factor for both …

[HTML][HTML] CACNA1C as a risk factor for schizotypal personality disorder and schizotypy in healthy individuals

P Roussos, MM McClure, EA Hazlett, AS New… - Psychiatry …, 2013 - ncbi.nlm.nih.gov
The CACNA1C gene codes for the pore-forming a1C subunit of the L-type voltage-gated
calcium channel and plays an important role in synaptic plasticity, memory formation …

Neurotrophin receptor activation rescues cognitive and synaptic abnormalities caused by hemizygosity of the psychiatric risk gene Cacna1c

CM Tigaret, TCE Lin, ER Morrell, L Sykes… - Molecular …, 2021 - nature.com
Genetic variation in CACNA1C, which encodes the alpha-1 subunit of CaV1. 2 L-type
voltage-gated calcium channels, is strongly linked to risk for psychiatric disorders including …

Common variants in CACNA1C and MDD susceptibility: A comprehensive metaanalysis

S Rao, Y Yao, C Zheng, J Ryan, C Mao… - American Journal of …, 2016 - Wiley Online Library
Major depressive disorder (MDD) is one of the most common psychiatric disorders with a
relatively high heritability (35–40%). Though rs1006737 in the CACNA1C gene showed …

Genes involved in neurodevelopment, neuroplasticity, and bipolar disorder: CACNA1C, CHRNA1, and MAPK1

M Calabrò, L Mandelli, C Crisafulli, A Sidoti… - …, 2017 - karger.com
Background: Bipolar disorder (BPD) is a common and severe mental disorder. The
involvement of genetic factors in the pathophysiology of BPD is well known. In the present …