Muscarinic and nicotinic cholinergic receptors and choline acetyltransferase activity were
studied in postmortem brain tissue from patients with histopathologically confirmed …

[3H] 3-Quinuclidinyl benzilate was used to characterize the muscarinic cholinergic receptor
binding in three regions of the normal human brain and in rat brain. In each of these tissues …

We have recently reported on the differential alterations of various cholinergic markers in
cortical and subcortical regions in Alzheimer's disease (AD). The main purpose of the …

Total muscarinic receptor levels, the levels of the subtypes exhibiting high and low affinity for
pirenzepine, and the highand lowaffinity agonist states of the receptor were investigated in …

The distribution of nicotinic and muscarinic receptor subtypes was examined in human brain
tissue obtained at autopsy from neurologically normal adult (50-60 years) individuals …

The main objective of the present study was to determine whether cholinergic markers
(choline acetyltransferase activity and nicotinic and muscarinic receptors) are altered in …

Abstract [3 H] Quinuclidinylbenzilate ([3 H] QNB) binding and choline acetyltransferase
(CAT) activity were studied in post-mortem brains from control and Parkinsonian subjects …

The cholinergic receptors are classically divided into two kinds, namely the nicotinic
acetylcholine receptor and the muscarinic acetyl-choline receptor. The existence of these …

Cholinergic receptors (muscarinic subtypes M1 and M2, and putative nicotinic binding) have
been examined in the hippocampus obtained at autopsy from a variety of patients with …

The total population of muscarinic receptors and a subpopulation of muscarinic receptors
with high affinity for agonists were measured with [3 H] quinuclidinyl benzilate and [3 H] …