Binding properties for the muscarinic antagonist quinuclidinyl benzilate (QNB), the nicotinic
antagonist tubocurarine and nicotine to crude synaptosomal fractions from mouse and rat …

The binding and regulation of selected muscarinic agonists to putative subtypes in rat
cerebral cortex and heart were studied. Parallel inhibition studies of [3H] pirenzepine ([3H] …

The anticholinergic antiparkinsonian drugs biperiden, benztropine, trihexyphenidyl,
methixene, and procyclidine were compared with atropine and pirenzepine, as well as with …

Muscarinic cholinergic receptors and choline acetyltransferase (ChAT) activity were studied
in postmortem brain tissue from patients with Huntington's disease and matched control …

The specific binding of [3 H] pirenzepine was investigated in homogenates of rat cerebral
cortex, cerebellar cortex, and heart. Specific binding of [3 H] pirenzepine in the cerebral …

The distribution and characteristics of M 1 and M 2 muscarinic cholinergic receptors as
defined by their affinity for the antagonist pizenzepine were studied in the human brain using …

Different effects of normal aging on muscarinic and nicotinic receptor subtypes were
observed in postmortem brain tissue from different regions of the human brain. A significant …

Neurotransmitter receptor binding for GABA, serotonin, cholinergic muscarinic and
dopamine receptors and choline acetyltransferase (ChAc) activity were measured in the …

Muscarinic receptor densities were measured in membranes prepared from rat cerebral
cortex using [3H] pirenzepine and [3H] quinuclidinyl benzilate. Isotherms of equilibrium …

We have investigated the localization of muscarinic cholinergic receptors in the brainstem of
eight patients free of neurological disease following quantitative autoradiography of …