The autoradiographic distribution of M1 and M2 muscarinic cholinergic binding sites was
studied in the striatum of the cat, monkey, and human, and concurrent binding assays were …

Previous studies have shown that muscarinic cholinergic agonists bind to 3 distinct receptor
sites in brain, each being distinguished by their affinity for the agonists. Antagonists, on the …

Regional cerebral muscarinic cholinergic receptor binding was quantified in normal young
and elderly subjects employing the muscarinic antagonist radioligand [11C] tropanyl …

In order to elucidate pharmacological characteristics of nicotinic receptors in the brain,
competitive binding of nicotine analogues or cholinergic agents to brain particles was …

Studies show [3H] PZ identified selectively a subpopulation of muscarinic binding sites
compared to classical antagonists like (-)-[3H] QNB in many central and peripheral tissues …

The distribution of M1 and M2 muscarine receptors in the rat brain was investigated by in
vitro autoradiography. Muscarine receptors were visualized after complete receptor …

The muscarinic cholinergic antagonist 3-quinuclidinyl benzilate (QNB) binds avidly but
reversibly to the muscarinic cholinergic recptor of mammalian brain and peripheral …

Muscarinic cholinergic receptor sites in cerebral blood vessels were analyzed directly by
using radioligand binding techniques with the specific muscarinic antagonist [3H] …

Quantitative measurements were made of choline acetyltransferase (CAT) activity,
acetylcholinesterase (AChE) acitivity and cholinergic muscarinic receptor binding ([3 H] …

The status of cholinergic receptors in dementia is related to the question of potential
cholinergic therapy. Whilst muscarinic receptor binding is generally reported to be normal or …