Ferroptosis: A double-edged sword

S Wang, Q Guo, L Zhou, X Xia - Cell Death Discovery, 2024 - nature.com
Ferroptosis represents a form of programmed cell death that is propelled by iron-dependent
lipid peroxidation, thereby being distinguished by the prominent features of iron …

Ferroptosis as a potential target for cancer therapy

Z Chen, W Wang, SR Abdul Razak, T Han… - Cell death & …, 2023 - nature.com
Ferroptosis is a recently discovered essential type of cell death that is mainly characterized
by iron overload and lipid peroxidation. Emerging evidence suggests that ferroptosis is a …

Ferroptosis: Emerging mechanisms, biological function, and therapeutic potential in cancer and inflammation

X Jin, J Tang, X Qiu, X Nie, S Ou, G Wu, R Zhang… - Cell Death …, 2024 - nature.com
Ferroptosis represents a distinct form of programmed cell death triggered by excessive iron
accumulation and lipid peroxidation-induced damage. This mode of cell death differentiates …

Ferroptosis in cancer: From molecular mechanisms to therapeutic strategies

Q Zhou, Y Meng, D Li, L Yao, J Le, Y Liu… - … and Targeted Therapy, 2024 - nature.com
Ferroptosis is a non-apoptotic form of regulated cell death characterized by the lethal
accumulation of iron-dependent membrane-localized lipid peroxides. It acts as an innate …

Ferroptosis: a dual-edged sword in tumour growth

X Zhao, X Li, Y Xu - Frontiers in Pharmacology, 2024 - frontiersin.org
Ferroptosis, a recently identified form of non-apoptotic cell death, is distinguished by its
dependence on iron-triggered lipid peroxidation and accumulation of iron. It has been linked …

[HTML][HTML] The Roles of Iron and Ferroptosis in Human Chronic Diseases

Y Shi, J Zhang, K Luo, S Pan, H Shi… - Cell Death and …, 2023 - intechopen.com
Ferroptosis, an iron-dependent novel type of cell death, has been characterized as an
excessive accumulation of lipid peroxides and reactive oxygen species. A growing number …

Cashing in on ferroptosis against tumor cells: Usher in the next chapter

MR Valashedi, N Najafi-Ghalehlou, A Nikoo… - Life Sciences, 2021 - Elsevier
Ferroptosis is a new type of non-apoptotic regulated cell death (RCD) driven by unrestricted
lethal lipid peroxidation, which is totally distinct from other forms of RCD in genetic and …

Crosstalk between ferroptosis and stress—Implications in cancer therapeutic responses

C Zhang, J Yu, C Yang, S Shang, X Lv, B Cui… - Cancer …, 2022 - Wiley Online Library
Ferroptosis is a newly discovered form of cell death that is characterized by the
accumulation of irondependent lipid peroxidation. Research on ferroptosis has seen …

Ferroptosis: mechanisms, biology and role in disease

X Jiang, BR Stockwell, M Conrad - Nature reviews Molecular cell …, 2021 - nature.com
The research field of ferroptosis has seen exponential growth over the past few years, since
the term was coined in 2012. This unique modality of cell death, driven by iron-dependent …

Ferroptosis: Final destination for cancer?

Z Ye, W Liu, Q Zhuo, Q Hu, M Liu, Q Sun… - Cell …, 2020 - Wiley Online Library
Ferroptosis is a recently defined, nonapoptotic, regulated cell death (RCD) process that
comprises abnormal metabolism of cellular lipid oxides catalysed by iron ions or iron …