Cancer is a leading cause of death in developed countries, and is on the rise in developing
countries due in part to a lack of prophylactic screening and non-universal access to medical …

Cholesterol/sphingolipid-rich membrane domains, known as lipid rafts or membrane rafts,
play a critical role in the compartmentalization of signaling pathways. Physical segregation …

Cell signaling does not apparently occur randomly over the cell surface, but it seems to be
integrated very often into cholesterol-rich membrane domains, termed lipid rafts. Membrane …

Lipid rafts are cholesterolenriched microdomains of the cell membrane and possess a
highly dynamic nature. They have been involved in various cellular functions including the …

Tumor biomarkers assist in the early detection of cancer, act as therapeutic targets for
intervention, and function as diagnostic indicators for the evaluation of therapeutic …

Purpose Lipid rafts are cholesterol enriched microdomains that colocalize signaling
pathways involved in cell proliferation, metastasis, and angiogenesis. We examined the …

Lipid rafts are tightly packed, cholesterol-and sphingolipid-enriched microdomains within the
plasma membrane that play important roles in many pathophysiologic processes. Rafts have …

Cancer is one of the most devastating disorders in our lives. Higher rate of proliferation than
death of cells is one of the essential factors for development of cancer. The dynamicity of cell …

Abstract etastatic progression is the cause of most cancer deaths. Host tumour cell
separation (fission) is accompanied by simultaneous acquisition of migrating capability of …

Abnormal lipid metabolism is common in breast cancer with the three main subtypes,
hormone receptor (HR) positive, human epidermal growth factor 2 (HER2) positive, and …