Objective To address heterogeneity complicating primary SS (pSS) clinical trials, research
and care by characterizing and clustering patients by their molecular phenotypes. Methods …

Background Primary Sjögren's syndrome (pSS) is a chronic systemic autoimmune disease
of the exocrine glands characterized by specific pathological features. Previous studies have …

Objectives Clinical presentation of primary Sjögren's syndrome (pSS) varies considerably. A
shortage of evidence-based objective markers hinders efficient drug development and most …

Sjögren's syndrome (SS) is an autoimmune disease characterized by lymphocytic infiltration
and destruction of salivary and lacrimal glands. The diagnosis of SS can be challenging due …

Objective Although symptom relief is a critical aspect for successful drug development in
Sjögren's disease, patient experiences with Sjögren'srelated symptoms are understudied …

Background Treatment of patients with Sjögren's syndrome (SjS) is a clinical challenge with
high unmet needs. Gene expression profiling and integrative network-based approaches to …

Objectives Multiomics study was conducted to elucidate the crucial molecular mechanisms
of primary Sjögren's syndrome (SS) pathology. Methods We generated multiple data set …

Context Primary Sjögren's syndrome (pSS) is a complex heterogeneous autoimmune
disease (AID) which can mimic rheumatoid arthritis (RA) or systemic lupus erythematosus …

Background Sjogren's syndrome (SS) is a heterogenous disease with various phenotypes.
We aimed to provide a relevant subclassification based on symptom-based clustering for …

Introduction The purpose of this study was to identify differentially expressed (DE) genes
and biological processes associated with changes in gene expression in primary Sjogren's …