Site of the ischemic penumbra as a predictor of potential for recovery of functions

AE Hillis, L Gold, V Kannan, L Cloutman, JT Kleinman… - Neurology, 2008 - AAN Enterprises
Background and Purpose: Diffusion–perfusion mismatch has been used to estimate
salvageable tissue and predict potential for recovery in acute stroke. Location of the …

“Diffusion-clinical mismatch” is associated with potential for early recovery of aphasia

LA Reineck, S Agarwal, AE Hillis - Neurology, 2005 - AAN Enterprises
Background: Diffusion-perfusion mismatch (perfusion-weighted imaging [PWI] abnormality
minus diffusion-weighted imaging [DWI] abnormality) can identify candidates for acute stroke …

Diffusion–perfusion mismatch: an opportunity for improvement in cortical function

M Motta, A Ramadan, AE Hillis, RF Gottesman… - Frontiers in …, 2015 - frontiersin.org
Objective: There has been controversy over whether diffusion–perfusion mismatch provides
a biomarker for the ischemic penumbra. In the context of clinical stroke trials, regions of the …

Change in perfusion in acute nondominant hemisphere stroke may be better estimated by tests of hemispatial neglect than by the National Institutes of Health Stroke …

AE Hillis, RJ Wityk, PB Barker, JA Ulatowski… - Stroke, 2003 - Am Heart Assoc
Background and Purpose—It has been reported that National Institutes of Health Stroke
Scale (NIHSS) scores correlate poorly with hypoperfused tissue measured by perfusion …

MR perfusion imaging reveals regions of hypoperfusion associated with aphasia and neglect

AE Hillis, PB Barker, NJ Beauchamp, B Gordon… - Neurology, 2000 - AAN Enterprises
Objective: To evaluate diffusion-weighted imaging (DWI) and MR perfusion imaging (MRPI)
as tools for identifying regions of infarct and hypoperfusion associated with aphasia and …

Relationships between infarct growth, clinical outcome, and early recanalization in diffusion and perfusion imaging for understanding stroke evolution (DEFUSE)

JM Olivot, M Mlynash, VN Thijs, S Kemp, MG Lansberg… - Stroke, 2008 - Am Heart Assoc
Background and Purpose—The purpose of this study was to determine the relationships
between ischemic lesion growth, recanalization, and clinical response in stroke patients with …

Prediction of infarct growth and neurologic deterioration in patients with positive perfusion–diffusion mismatch

CT Hong, Y Sun, CJ Lu, HC Shin, RC Chen - Clinical neurology and …, 2012 - Elsevier
BACKGROUND: To assess the value of baseline clinical severity and perfusion–diffusion
mismatch as predictors for further infarct growth and clinical outcome. METHODS: Patients …

Clinical-diffusion mismatch predicts the putative penumbra with high specificity

J Prosser, K Butcher, L Allport, M Parsons… - Stroke, 2005 - Am Heart Assoc
Background and Purpose—Perfusion-diffusion (PWI-DWI) mismatch may represent the
ischemic penumbra. The complexities associated with perfusion-weighted imaging (PWI) …

Estimating perfusion deficits in acute stroke patients without perfusion imaging

D Reyes, AN Simpkins, E Hitomi, JK Lynch, AW Hsia… - Stroke, 2022 - Am Heart Assoc
Background: Perfusion weighted imaging (PWI) is critical for determining whether stroke
patients presenting in an extended time window are candidates for mechanical …

Relationship between severity of MR perfusion deficit and DWI lesion evolution

VN Thijs, A Adami, T Neumann–Haefelin, ME Moseley… - Neurology, 2001 - AAN Enterprises
Objective: To assess whether a quantitative analysis of the severity of the early perfusion
deficit on MRI in acute ischemic stroke predicts the evolution of the perfusion/diffusion …