Autophagy was considered as a double-edged sword that might cooperate, aggravate, or
antagonize apoptosis. We found that the sonodynamic therapy (SDT) in low dosage induced …

The ultrasound-triggered sonodynamic therapy (SDT) with high tissue penetration, high
spatiotemporal selectivity, and non-invasive advantages represents an emerging approach …

Sonodynamic therapy (SDT) is a noninvasive technique for local antitumor treatment;
however, its clinical application is often limited by the low tumor accumulation of SDT …

The tumor microenvironment (TME) featured by immunosuppression and hypoxia is pivotal
to cancer deterioration and metastasis. Thus, regulating the TME to improve cancer cell …

Sonodynamic therapy (SDT) is a promising strategy for tumor treatment that satisfies all
requirements of penetrating deep-seated tissues without causing additional trauma …

Sonodynamic therapy (SDT) is a highly attractive therapy due to its advantages of being non-
invasive and having good penetration depth, but tumor hypoxia extremely restricts its …

Sonodynamic therapy (SDT) shows tremendous potential to induce immunogenic cell death
(ICD) and activate antitumor immunity. However, it can aggravate hypoxia and release …

Limited penetration of chemotherapeutic drugs through the blood brain barrier (BBB), and
the increased chemo-resistance of glioma cells due to macroautophagy/autophagy, result in …

Fabrication of ingenious nanomedicines to penetrate the blood–brain barrier (BBB) and
blood–brain–tumor barrier (BBTB) for efficient glioblastoma (GBM) therapy remains a big …

Despite advances in drug delivery systems (DDSs), the stimuli-responsive controlled
release DDSs with high spatial/temporal resolution are still the best choice. Herein, a novel …