[HTML][HTML] Ferroptosis: a dual-edged sword in tumour growth

X Zhao, X Li, Y Xu - Frontiers in Pharmacology, 2024 - frontiersin.org
Ferroptosis, a recently identified form of non-apoptotic cell death, is distinguished by its
dependence on iron-triggered lipid peroxidation and accumulation of iron. It has been linked …

[HTML][HTML] Recent advances of ferroptosis in tumor: From biological function to clinical application

S Hu, Y Chu, X Zhou, X Wang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Ferroptosis is a recently recognized form of cell death with distinct features in terms of
morphology, biochemistry, and molecular mechanisms. Unlike other types of cell death …

Ferroptosis as ultimate target of cancer therapy

Y Motooka, S Toyokuni - Antioxidants & Redox Signaling, 2023 - liebertpub.com
Significance: The significance of ferroptosis in cancer therapeutics has now been unveiled.
Specific ferroptosis inducers are expected as a promising strategy for cancer treatment …

Ferroptosis in Cancer Therapy: Mechanisms, Small Molecule Inducers, and Novel Approaches

YL Luo, XY Bai, L Zhang, QQ Hu, N Zhang… - Drug Design …, 2024 - Taylor & Francis
Ferroptosis, a unique form of programmed cell death, is initiated by an excess of iron
accumulation and lipid peroxidation-induced damage. There is a growing body of evidence …

Ferroptosis: a new promising target for lung cancer therapy

R Xiong, R He, B Liu, W Jiang, B Wang… - Oxidative Medicine …, 2021 - Wiley Online Library
Ferroptosis is a new type of regulatory cell death that differs from autophagy, apoptosis,
necrosis, and pyroptosis; it is caused primarily by the accumulation of iron and lipid …

[HTML][HTML] Ferroptosis in life: To be or not to be

L Xu, Y Liu, X Chen, H Zhong, Y Wang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Ferroptosis is a novel type of programmed cell death, characterized by a dysregulated iron
metabolism and accumulation of lipid peroxides. It features the alteration of mitochondria …

[HTML][HTML] Targeting ferroptosis pathway to combat therapy resistance and metastasis of cancer

X Liu, Y Zhang, X Wu, F Xu, H Ma, M Wu… - Frontiers in …, 2022 - frontiersin.org
Ferroptosis is an iron-dependent regulated form of cell death caused by excessive lipid
peroxidation. This form of cell death differed from known forms of cell death in morphological …

[HTML][HTML] Insights into ferroptosis, a novel target for the therapy of cancer

HT Wang, J Ju, SC Wang, YH Zhang, CY Liu… - Frontiers in …, 2022 - frontiersin.org
Ferroptosis is a new form of programmed cell death (PCD) characterized by an excess iron
accumulation and subsequent unbalanced redox states. Ferroptosis is different from the …

Research progress on the mechanism of ferroptosis and its clinical application

J Xia, H Si, W Yao, C Li, G Yang, Y Tian… - Experimental Cell …, 2021 - Elsevier
Ferroptosis is a mode of cell death dependent on iron ions, which is mainly induced by the
decrease of the biological activity of glutathione peroxidase or the accumulation of lipid …

The mechanisms and therapeutic targets of ferroptosis in cancer

L Ye, F Jin, SK Kumar, Y Dai - Expert opinion on therapeutic targets, 2021 - Taylor & Francis
Introduction Ferroptosis, a form of programmed cell death, is mediated primarily by lipid
peroxidation via a unique iron-dependent process. The mechanisms of ferroptosis involve …