The therapeutic effects of low-intensity pulsed ultrasound in musculoskeletal soft tissue injuries: Focusing on the molecular mechanism

H Qin, L Du, Z Luo, Z He, Q Wang, S Chen… - … in Bioengineering and …, 2022 - frontiersin.org
Musculoskeletal soft tissue injuries are very common and usually occur during both sporting
and everyday activities. The intervention of adjuvant therapies to promote tissue …

[HTML][HTML] Low-intensity pulsed ultrasound promotes skeletal muscle regeneration via modulating the inflammatory immune microenvironment

H Qin, Z Luo, Y Sun, Z He, B Qi, Y Chen… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Background: Low-intensity pulsed ultrasound (LIPUS, a form of mechanical stimulation) can
promote skeletal muscle functional repair, but a lack of mechanistic understanding of its …

[HTML][HTML] Ultrasound as a stimulus for musculoskeletal disorders

N Zhang, SKH Chow, KS Leung, WH Cheung - Journal of orthopaedic …, 2017 - Elsevier
Ultrasound is an inaudible form of acoustic sound wave at 20 kHz or above that is widely
used in the medical field with applications including medical imaging and therapeutic …

Using low-intensity pulsed ultrasound to improve muscle healing after laceration injury: an in vitro and in vivo study

YS Chan, KY Hsu, CH Kuo, SD Lee, SC Chen… - Ultrasound in medicine …, 2010 - Elsevier
The purpose of this study was to determine whether low-intensity pulsed ultrasound (LIPUS)
could enhance the regeneration of myofibers and shorten the healing time in injured muscle …

Low-intensity pulsed ultrasound augments tendon, ligament, and bone–soft tissue healing in preclinical animal models: a systematic review

WC Lai, BC Iglesias, BJ Mark, D Wang - Arthroscopy: The Journal of …, 2021 - Elsevier
Purpose To appraise the available animal and human studies investigating low-intensity
pulsed ultrasound stimulation (LIPUS) on tendon, ligament, and bone–soft tissue (B-ST) …

[HTML][HTML] Mode & mechanism of low intensity pulsed ultrasound (LIPUS) in fracture repair

A Harrison, S Lin, N Pounder, Y Mikuni-Takagaki - Ultrasonics, 2016 - Elsevier
It has been 30 years since the first level one clinical trial demonstrated low intensity pulsed
ultrasound (LIPUS) could accelerate fracture repair. Since 1994 numerous investigations …

Effects of LowIntensity Pulsed Ultrasound in Tendon Injuries

Y Li, W Li, X Liu, X Liu, B Zhu, S Guo… - … of Ultrasound in …, 2023 - Wiley Online Library
Tendon injuries are the most common soft tissue injuries, caused by tissue overuse and age
related degeneration. However, the tendon repair process is slow and inefficient due to the …

Low-intensity pulsed ultrasound therapy: a potential strategy to stimulate tendon-bone junction healing

Z Ying, T Lin, S Yan - Journal of Zhejiang University SCIENCE B, 2012 - Springer
Incorporation of a tendon graft within the bone tunnel represents a challenging clinical
problem. Successful anterior cruciate ligament (ACL) reconstruction requires solid healing of …

[HTML][HTML] LIPUS promotes synthesis and secretion of extracellular matrix and reduces cell apoptosis in human osteoarthritis through upregulation of SOX9 expression

W Ding, D Du, S Chen - International journal of clinical and …, 2020 - ncbi.nlm.nih.gov
Increasing studies have illustrated that low-intensity pulsed ultrasound (LIPUS) has a
therapeutic effect in experimental animal models of osteoarthritis (OA). However, the …

[HTML][HTML] The science of ultrasound therapy for fracture healing

GJ Della Rocca - Indian journal of orthopaedics, 2009 - ncbi.nlm.nih.gov
Fracture healing involves a complex interplay of cellular processes, culminating in bridging
of a fracture gap with bone. Fracture healing can be compromised by numerous exogenous …