Brain plasticity can be defined as the ability of local and extended neural systems to
organize either the structure and/or the function of their connectivity patterns to better adapt …

Nicotine abuse and addiction is a major health liability. Nicotine, an active alkaloid in
tobacco, is self-administered by animals and produces cellular adaptations in brain regions …

Previous studies from our laboratory showed that baclofen (BAC, GABAB receptor agonist)
prevented the behavioral and neurochemical alterations of nicotine (NIC) withdrawal …

Vagus nerve stimulation (VNS) delivered during motor rehabilitation enhances recovery
from a wide array of neurological injuries and was recently approved by the US FDA for …

Rationale Nicotine can enhance attentional performance in humans, a property that may be
of therapeutic utility. Objectives To identify brain sites mediating nicotine-induced attentional …

Loss of basal forebrain cholinergic innervation of the hippocampus and severe neuronal
loss within the hippocampal CA1 region are early hallmarks of Alzheimer's disease, and are …

Although neurotransmitter-based hypotheses still prevail current thinking about the
mechanism of action of psychotropic drugs, recent insight into the pathophysiology of …

The application of medications with a well-defined mode of action on a neurotransmitter or
neuromodulator of the central nervous system (CNS) can be utilized to test the pharmaco …

Background: The potential of non-invasive brain stimulation (NIBS) for studying, and
inducing, functionally relevant neuroplasticity is dependent on protocols that can induce …

Over 70 million European pregnant women are smokers during their child-bearing years.
Consumption of tobacco-containing products during pregnancy is associated with several …