KIF2C: a novel link between Wnt/β-catenin and mTORC1 signaling in the pathogenesis of hepatocellular carcinoma
S Wei, M Dai, C Zhang, K Teng, F Wang, H Li… - Protein & …, 2021 - academic.oup.com
Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and is the
fourth-leading cause of cancer-related deaths worldwide. HCC is refractory to many …
fourth-leading cause of cancer-related deaths worldwide. HCC is refractory to many …
Upregulation of kinesin family member 4A enhanced cell proliferation via activation of Akt signaling and predicted a poor prognosis in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the third most frequent cause of cancer-related death
worldwide, and the molecular pathogenesis and development of HCC are largely unknown …
worldwide, and the molecular pathogenesis and development of HCC are largely unknown …
KIF11 promotes proliferation of hepatocellular carcinoma among patients with liver cancers
ZD Hu, Y Jiang, HM Sun, J Wang… - BioMed research …, 2021 - Wiley Online Library
Background. Hepatocellular carcinoma (HCC) lacks effective treatments and has a poor
prognosis. Therefore it is needed to develop more effective drug targets. Kinesin family …
prognosis. Therefore it is needed to develop more effective drug targets. Kinesin family …
Upregulate KIF4A enhances proliferation, invasion of hepatocellular carcinoma and indicates poor prognosis across human cancer types
Hepatocellular carcinoma (HCC) is one of the most aggressive and heterogeneous cancers
worldwide. Herein, we demonstrate KIF4A (Chromosome-associated kinesin KIF4A) as a …
worldwide. Herein, we demonstrate KIF4A (Chromosome-associated kinesin KIF4A) as a …
Kinesin superfamily protein expression and its association with progression and prognosis in hepatocellular carcinoma
J Chen, S Li, S Zhou, S Cao, Y Lou… - Journal of Cancer …, 2017 - journals.lww.com
Objectives: In this study, we characterized the expression of 32 other kinesin superfamily
proteins (KIFs) and analyzed their association with the progression and prognosis of …
proteins (KIFs) and analyzed their association with the progression and prognosis of …
[HTML][HTML] Kinesin family members KIF2C/4A/10/11/14/18B/20A/23 predict poor prognosis and promote cell proliferation in hepatocellular carcinoma
X Li, W Huang, W Huang, T Wei, W Zhu… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Kinesin superfamily proteins (KIFs) comprise a family of molecular motors that transport
membranous organelles and protein complexes in a microtubule-and ATP-dependent …
membranous organelles and protein complexes in a microtubule-and ATP-dependent …
[HTML][HTML] Kinesin family member 15 promotes cancer stem cell phenotype and malignancy via reactive oxygen species imbalance in hepatocellular carcinoma
Q Li, J Qiu, H Yang, G Sun, Y Hu, D Zhu, Z Deng… - Cancer letters, 2020 - Elsevier
The development and progression of hepatocellular carcinoma (HCC) is associated with the
presence of cancer stem cells (CSCs). In the present study, kinesin family member 15 …
presence of cancer stem cells (CSCs). In the present study, kinesin family member 15 …
KIFC1 is activated by TCF-4 and promotes hepatocellular carcinoma pathogenesis by regulating HMGA1 transcriptional activity
K Teng, S Wei, C Zhang, J Chen, J Chen… - Journal of Experimental …, 2019 - Springer
Background Kinesins play important roles in the development and progression of many
human cancers. The functions and underlying mechanisms of kinesin family member C1 …
human cancers. The functions and underlying mechanisms of kinesin family member C1 …
The role of kinesin KIF18A in the invasion and metastasis of hepatocellular carcinoma
W Luo, M Liao, Y Liao, X Chen, C Huang, J Fan… - World journal of surgical …, 2018 - Springer
Background KIF18A is associated with a variety of tumours; however, the specific
mechanism of action of KIF18A in hepatocellular carcinoma (HCC) remains unclear. In this …
mechanism of action of KIF18A in hepatocellular carcinoma (HCC) remains unclear. In this …
[HTML][HTML] KIF20A promotes cellular malignant behavior and enhances resistance to chemotherapy in colorectal cancer through regulation of the JAK/STAT3 signaling …
M Xiong, K Zhuang, Y Luo, Q Lai, X Luo, Y Fang… - Aging (albany …, 2019 - ncbi.nlm.nih.gov
Background/Aims: Kinesin family member 20A (KIF20A) is upregulated in multiple cancers
and plays important roles in promoting malignant behavior, whereas its exact role in CRC …
and plays important roles in promoting malignant behavior, whereas its exact role in CRC …
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