Early pregnancy immune biomarkers in peripheral blood may predict preeclampsia

MDS Garcia, Y Mobley, J Henson, M Davies… - Journal of reproductive …, 2018 - Elsevier
We performed a prospective cohort study in 197 pregnant women. Peripheral blood was
collected between 5 and 16 weeks of gestation. Intracellular cytokine analysis and …

First and second trimester immune biomarkers in preeclamptic and normotensive women

BD Taylor, RB Ness, MA Klebanoff, R Zoh… - … An International Journal …, 2016 - Elsevier
Introduction Circulating immune markers may be associated with preeclampsia but further
investigations in early pregnancy and among preeclampsia subtypes are warranted. We …

Mid-pregnancy circulating immune biomarkers in women with preeclampsia and normotensive controls

BD Taylor, G Tang, RB Ness, J Olsen… - … An International Journal …, 2016 - Elsevier
Objectives To determine if mid-pregnancy circulating immune biomarkers are associated
with preeclampsia. Study design Nested case-control study of 410 preeclamptic women and …

Cytokine mapping of sera from women with preeclampsia and normal pregnancies

Y Jonsson, M Rubèr, L Matthiesen, G Berg… - Journal of reproductive …, 2006 - Elsevier
INTRODUCTION: Preeclampsia is a pregnancy-specific syndrome. The immune system in
preeclampsia is changed with an increased innate activity and there is a hypothesis of a shift …

IL-10, TNF-α & IFN-γ: potential early biomarkers for preeclampsia

A Kumar, N Begum, S Prasad, S Agarwal, S Sharma - Cellular immunology, 2013 - Elsevier
The present study was designed to evaluate levels of IL4, IL10, TNF-α & IFN-γ at early
second trimester and 24 h from delivery to assess potential correlation of cytokine variation …

Preeclampsia is characterized by fetal NK cell activation and a reduction in regulatory T cells

AI Loewendorf, TA Nguyen… - American Journal of …, 2015 - Wiley Online Library
Problem Preeclampsia affects 3–17% of pregnancies worldwide and has serious
consequences for both the mother and the fetus. As maternal–fetal immune tolerance is …

Cytokine expression in peripheral blood lymphocytes indicates a switch to Thelper cells in patients with preeclampsia

DT Rein, T Schöndorf, UJ Göhring… - Journal of reproductive …, 2002 - Elsevier
We sought to determine whether cytokine expression in peripheral blood mononuclear cells
is altered in patients with preeclampsia and in patients with a history of recurrent …

Increased prevalence of IL17producing peripheral blood lymphocytes in preeclampsia

G Toldi, J Rigó Jr, B Stenczer… - American journal of …, 2011 - Wiley Online Library
Citation Toldi G, Rigó J Jr, Stenczer B, Vásárhelyi B, Molvarec A. Increased prevalence of IL
17producing peripheral blood lymphocytes in preeclampsia. Am J Reprod Immunol 2011; …

Association of proand antiinflammatory cytokines in preeclampsia

R Aggarwal, AK Jain, P Mittal, M Kohli… - Journal of clinical …, 2019 - Wiley Online Library
Introduction The proand antiinflammatory cytokines play crucial role in the development
and functions of placenta. Any changes in these cytokines may be associated with many …

T cell immunity and the etiology and pathogenesis of preeclampsia

S Saito, S Tsuda, A Nakashima - Journal of reproductive immunology, 2023 - Elsevier
Preeclampsia is more common in nulliparous women, their first pregnancies with a new
partner in multiparous women, pregnant women with short duration of cohabitation, and in …