Microscopy is a fundamental technology driving new biological discoveries. Today
microscopy allows a large number of images to be acquired using, for example, High …

High content cellbased screens are rapidly gaining popularity in the context of neuronal
regeneration studies. To analyze neuronal morphology, automatic image analysis pipelines …

Using primary cell culture to screen for changes in neuronal morphology requires
specialized analysis software. We developed NeuronMetrics™ for semi-automated …

Background: To investigate the intricate nervous processes involved in many biological
activities by computerized image analysis, accurate and reproducible labeling and …

Automated analyses of neuronal morphology are important for quantifying connectivity and
circuitry in vivo, as well as in high content imaging of primary neuron cultures. The currently …

Automating the analysis of neurons in culture represents a key aspect of the search for
neuroactive compounds. A number of commercial neurite analysis software packages tend …

The study of neuronal morphology and neurite outgrowth has been enhanced by the
combination of imaging informatics and high content screening, in which thousands of …

Background Neurite outgrowth is a metric widely used to assess the success of in vitro
neural stem cell differentiation or neuron reprogramming protocols and to evaluate high …

Background For the investigation of the molecular mechanisms involved in neurite
outgrowth and differentiation, accurate and reproducible segmentation and quantification of …

Manual neuron tracing is a very laborintensive task. In the drug screening context, the
sheer number of images to process means that this approach is unrealistic. Moreover, the …