Gene–environment interplay in the etiology of psychosis

A Zwicker, EM Denovan-Wright, R Uher - Psychological medicine, 2018 - cambridge.org
Schizophrenia and other types of psychosis incur suffering, high health care costs and loss
of human potential, due to the combination of early onset and poor response to treatment …

[HTML][HTML] Understanding what causes schizophrenia: a developmental perspective

JH Gilmore - American Journal of Psychiatry, 2010 - Am Psychiatric Assoc
Understanding what causes schizophrenia is becoming harder and harder. We know that
schizophrenia has genetic causes, since the most significant risk factor is having a first …

Early and late environmental risk factors for schizophrenia

C McDonald, RM Murray - Brain Research Reviews, 2000 - Elsevier
Although a high proportion of liability to schizophrenia is under genetic control, a number of
environmental risk factors have been identified. The earliest of these are complications of …

Comments on risk for schizophrenia

M Weiser, M Davidson, S Noy - Schizophrenia research, 2005 - Elsevier
Recent developments have significantly furthered understanding of genetic and
environmental factors affecting risk for schizophrenia. Environmental effects, such as …

[HTML][HTML] Environmental risk factors for schizophrenia and bipolar disorder and their relationship to genetic risk: current knowledge and future directions

N Robinson, SE Bergen - Frontiers in genetics, 2021 - frontiersin.org
Schizophrenia (SZ) and bipolar disorder (BD) are severe psychiatric disorders which result
from complex interplay between genetic and environmental factors. It is well-established that …

Molecular genetic gene–environment studies using candidate genes in schizophrenia: a systematic review

G Modinos, C Iyegbe, D Prata, M Rivera… - Schizophrenia …, 2013 - Elsevier
The relatively high heritability of schizophrenia suggests that genetic factors play an
important role in the etiology of the disorder. On the other hand, a number of environmental …

Genes, environment and schizophrenia

MT Tsuang, WS Stone, SV Faraone - The British Journal of …, 2001 - cambridge.org
BackgroundData from family, twin and adoption studies show overwhelming evidence of a
substantial genetic component in schizophrenia and although molecular genetic studies …

Environmental studies of schizophrenia through the prism of epigenetics

G Oh, A Petronis - Schizophrenia bulletin, 2008 - academic.oup.com
Traditionally, etiological research of schizophrenia has been focused on elucidating
predisposing genes and environmental risk factors. While numerous putative environmental …

Prenatal factors in schizophrenia

S King, A St-Hilaire… - Current Directions in …, 2010 - journals.sagepub.com
The purpose of this review is to summarize the current state of knowledge on how
nongenetic factors occurring before, during, or soon after birth are related to schizophrenia …

Genetically mediated vulnerability to schizophrenia

CA Prescott, II Gottesman - Psychiatric Clinics of North America, 1993 - Elsevier
Family, twin, and adoption studies have firmly established the genetic basis for a majority of
cases of schizophrenia. Several other psychiatric disorders probably represent alternative …