Cholinesterases: new roles in brain function and in Alzheimer's disease
E Giacobini - Neurochemical research, 2003 - Springer
The most important therapeutic effect of cholinesterase inhibitors (ChEI) on approximately
50% of Alzheimer's disease (AD) patients is to stabilize cognitive function at a steady level …
50% of Alzheimer's disease (AD) patients is to stabilize cognitive function at a steady level …
Pharmacological drug treatment of Alzheimer disease: the cholinergi hypothesis revisited
CJ Ladner, JM Lee - Journal of neuropathology and …, 1998 - search.proquest.com
INTRODUCTION Alzheimer disease (AD) is a neurodegenerative disease affecting between
Solo and 10% of the population (1) over the age of 65. Individuals with AD exhibit profound …
Solo and 10% of the population (1) over the age of 65. Individuals with AD exhibit profound …
Effects of rivastigmine on behavioral and psychological symptoms of dementia in Alzheimer's disease
SI Finkel - Clinical therapeutics, 2004 - Elsevier
Background: The presence of certain behavioral and psychological symptoms (eg, paranoia,
hallucinations, aggression, activity disturbances) in Alzheimer's disease (AD) may predict …
hallucinations, aggression, activity disturbances) in Alzheimer's disease (AD) may predict …
Rivastigmine for the treatment of dementia and visual hallucinations associated with Parkinson's disease: a case series
R Bullock, A Cameron - Current medical research and opinion, 2002 - Taylor & Francis
Parkinson's disease patients may suffer from cognitive impairment and behavioural
problems such as apathy, personality changes, speech disturbances and visual …
problems such as apathy, personality changes, speech disturbances and visual …
Correlates of response to acetylcholinesterase inhibitor therapy in Alzheimer's disease
KL Lanctôt, N Herrmann, MM LouLou - Journal of Psychiatry and …, 2003 - jpn.ca
Cholinesterase inhibitors improve cognition and behaviour in some patients with
Alzheimer's disease (AD). Studies that have focused on methods to predict response to …
Alzheimer's disease (AD). Studies that have focused on methods to predict response to …
[HTML][HTML] Rivastigmine for dementia associated with Parkinson's disease
Background Cholinergic deficits are prominent in patients who have dementia associated
with Parkinson's disease. We investigated the effects of the dual cholinesterase inhibitor …
with Parkinson's disease. We investigated the effects of the dual cholinesterase inhibitor …
Efficacy and safety of cholinesterase inhibitors in Alzheimer's disease: a meta-analysis
KL Lanctôt, N Herrmann, KK Yau, LR Khan, BA Liu… - Cmaj, 2003 - Can Med Assoc
Background: Cholinesterase inhibitors (ChEIs) are the only drugs marketed for the treatment
of Alzheimer's disease. Despite numerous randomized controlled trials, the efficacy and …
of Alzheimer's disease. Despite numerous randomized controlled trials, the efficacy and …
Current treatments for Alzheimer's disease: cholinesterase inhibitors
RS Doody - Journal of Clinical Psychiatry, 2003 - psychiatrist.com
The current recommended standard of care for the symptomatic treatment of mild to
moderate Alzheimer's disease is cholinesterase inhibitors. In short-and long-term studies …
moderate Alzheimer's disease is cholinesterase inhibitors. In short-and long-term studies …
Development of cholinergic drugs for the treatment of Alzheimer's disease
CA Johns, V Haroutunian… - Drug Development …, 1985 - Wiley Online Library
Alzheimer's Disease (AD) is characterized neurochemically by a profound loss of choline
acetyl transferase activity and histologically by a selective degeneration of cholinergic …
acetyl transferase activity and histologically by a selective degeneration of cholinergic …
Discontinuation, efficacy, and safety of cholinesterase inhibitors for Alzheimer's disease: a meta-analysis and meta-regression of 43 randomized clinical trials enrolling …
L Blanco-Silvente, X Castells, M Saez… - International Journal …, 2017 - academic.oup.com
Background: We investigated the effect of cholinesterase inhibitors on all-cause
discontinuation, efficacy and safety, and the effects of study design-, intervention-, and …
discontinuation, efficacy and safety, and the effects of study design-, intervention-, and …