Contemporary outcomes in patients with long QT syndrome

RK Rohatgi, A Sugrue, JM Bos, BC Cannon… - Journal of the American …, 2017 - jacc.org
Abstract Background: Long QT syndrome (LQTS) is a potentially lethal cardiac
channelopathy with a 1% to 5% annual risk of LQTS-triggered syncope, aborted cardiac …

Risk of life-threatening cardiac events among patients with long QT syndrome and multiple mutations

J Mullally, I Goldenberg, AJ Moss, CM Lopes… - Heart Rhythm, 2013 - Elsevier
BACKGROUND: Patients with long QT syndrome (LQTS) who harbor multiple mutations
(ie≥ 2 mutations in≥ 1 LQTS-susceptibility gene) may experience increased risk for life …

Long QT syndrome

I Goldenberg, W Zareba, AJ Moss - Current problems in cardiology, 2008 - Elsevier
The hereditary Long QT syndrome (LQTS) is a genetic channelopathy with variable
penetrance that is associated with increased propensity for polymorphic ventricular …

Implantable cardioverter defibrillator therapy for congenital long QT syndrome: a single-center experience

JM Horner, M Kinoshita, TL Webster, CM Haglund… - Heart Rhythm, 2010 - Elsevier
BACKGROUND: Long QT syndrome's (LQTS) marked heterogeneity necessitates both
evidence-based and individualized therapeutic approaches. OBJECTIVE: This study sought …

The long QT syndrome

J Vohra - Heart, Lung and Circulation, 2007 - Elsevier
The long QT syndrome (LQTS) is a genetically transmitted cardiac arrhythmia due to ion
channel protein abnormalities, which affects the transport of potassium and sodium ions …

Clinical aspects of type 3 long-QT syndrome: an international multicenter study

AAM Wilde, AJ Moss, ES Kaufman, W Shimizu… - Circulation, 2016 - Am Heart Assoc
Background: Risk stratification in patients with type 3 long-QT syndrome (LQT3) by clinical
and genetic characteristics and effectiveness of β-blocker therapy has not been studied …

Diagnostic miscues in congenital long-QT syndrome

NW Taggart, CM Haglund, DJ Tester, MJ Ackerman - Circulation, 2007 - Am Heart Assoc
Background—Long-QT syndrome (LQTS) is a potentially lethal cardiac channelopathy that
can be mistaken for palpitations, neurocardiogenic syncope, and epilepsy. Because of …

Long QT syndrome in adults

AJ Sauer, AJ Moss, S McNitt, DR Peterson… - Journal of the American …, 2007 - jacc.org
Objectives: The aims of this study were: 1) to evaluate risk factors influencing the clinical
course of mutation-confirmed adult patients with long QT syndrome (LQTS), 2) to study life …

Clinical aspects of the three major genetic forms of long QT syndrome (LQT 1, LQT 2, LQT 3)

V Kutyifa, UA Daimee, S McNitt… - Annals of …, 2018 - Wiley Online Library
Background A comprehensive report on the clinical course of the three major genotypes of
the long QT syndrome (LQTS) in a large US patient cohort is lacking. Methods Our study …

Mutation and gender-specific risk in type 2 long QT syndrome: implications for risk stratification for life-threatening cardiac events in patients with long QT syndrome

D Migdalovich, AJ Moss, CM Lopes, J Costa, G Ouellet… - Heart rhythm, 2011 - Elsevier
BACKGROUND: Men and women with type 2 long QT syndrome (LQT2) exhibit time-
dependent differences in the risk for cardiac events. We hypothesized that data regarding …