Abstract Background Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) is a
multifunctional protease implicated in metastatic progression ostensibly due to its ability to …

Membrane-type 1 matrix metalloproteinase (MT1-MMP/MMP-14) has been believed a key
enzyme in tumor invasion, because it is expressed in a variety of malignant human tumors …

Degradation of extracellular matrix (ECM) is one of the first steps in tumor invasion and
metastasis. Matrix metalloproteinases (MMP) have been strongly implicated in this step …

Membrane-type matrix metalloproteinases (MT-MMP) constitute a subfamily of six distinct
membrane-associated MMPs. Although the contribution of MT1-MMP during different steps …

Membrane-type 1 matrix metalloproteinase (MT1-MMP) is a zinc-dependent type-I
transmembrane metalloproteinase involved in pericellular proteolysis, migration and …

Matrix metalloproteinases (MMPs) are believed to play a pivotal role in malignant behavior
of cancer cells such as rapid tumor growth, invasion, and metastasis by degrading …

Membranetype 1 matrix metalloproteinase (MT1MMP), a powerful modulator of the
pericellular environment, promotes migration, invasion, and proliferation of cells. To perform …

Membrane-type 1 matrix metalloproteinase (MT1-MMP) is an integral membrane proteinase
that is frequently expressed in malignant cancer cells and has potent invasion-promoting …

Membrane-type I matrix metalloproteinase (MT1-MMP) is associated with multiple forms of
cancer including mammary cancer. To directly evaluate the significance of MT1-MMP …

Background Recent evidence suggests that vascular endothelial growth factor-C (VEGF-C)-
dependent tumour production promotes lymphangiogenesis, while membrane-type matrix 1 …