The psychiatric vulnerability gene CACNA1C and its sex-specific relationship with personality traits, resilience factors and depressive symptoms in the general …
J Strohmaier, M Amelang, LA Hothorn, SH Witt… - Molecular …, 2013 - nature.com
Genome-wide association studies have reported an association between the A-allele of
rs1006737 within CACNA1C and affective disorders and schizophrenia. The aim of the …
rs1006737 within CACNA1C and affective disorders and schizophrenia. The aim of the …
Replication of brain function effects of a genome-wide supported psychiatric risk variant in the CACNA1C gene and new multi-locus effects
S Erk, A Meyer-Lindenberg, DEJ Linden, T Lancaster… - Neuroimage, 2014 - Elsevier
Variation in the CACNA1C gene has consistently been associated with psychosis in
genome wide association studies. We have previously shown in a sample of n= 110 healthy …
genome wide association studies. We have previously shown in a sample of n= 110 healthy …
[HTML][HTML] The genome-wide supported CACNA1C gene polymorphisms and the risk of schizophrenia: an updated meta-analysis
Y Liu, X Wu, X Xia, J Yao, B Wang - BMC medical genetics, 2020 - Springer
Abstract Background The CACNA1C gene was defined as a risk gene for schizophrenia in a
large genome-wide association study of European ancestry performed by the Psychiatric …
large genome-wide association study of European ancestry performed by the Psychiatric …
Mood disorder susceptibility gene CACNA1C modifies mood-related behaviors in mice and interacts with sex to influence behavior in mice and diagnosis in humans
DT Dao, PB Mahon, X Cai, CE Kovacsics… - Biological …, 2010 - Elsevier
BACKGROUND:: Recent genome-wide association studies have associated polymorphisms
in the gene CACNA1C, which codes for Cav1. 2, with a bipolar disorder and depression …
in the gene CACNA1C, which codes for Cav1. 2, with a bipolar disorder and depression …
A common CACNA1C gene risk variant has sex-dependent effects on behavioral traits and brain functional activity
H Takeuchi, H Tomita, Y Taki, Y Kikuchi, C Ono… - Cerebral …, 2019 - academic.oup.com
Genome-wide association studies have suggested that allelic variations in the CACNA1C
gene confer susceptibility to schizophrenia and bipolar disorder only in women. Here we …
gene confer susceptibility to schizophrenia and bipolar disorder only in women. Here we …
CACNA1C, schizophrenia and major depressive disorder in the Han Chinese population
BackgroundCommon psychiatric disorders are highly heritable, indicating that genetic
factors play an important role in their aetiology. The CACNA1C gene, which codes for …
factors play an important role in their aetiology. The CACNA1C gene, which codes for …
Common variants in CACNA1C and MDD susceptibility: A comprehensive metaanalysis
Major depressive disorder (MDD) is one of the most common psychiatric disorders with a
relatively high heritability (35–40%). Though rs1006737 in the CACNA1C gene showed …
relatively high heritability (35–40%). Though rs1006737 in the CACNA1C gene showed …
[HTML][HTML] Effects of the CACNA1C risk allele on neurocognition in patients with schizophrenia and healthy individuals
H Hori, N Yamamoto, T Fujii, T Teraishi, D Sasayama… - Scientific reports, 2012 - nature.com
Recent genetic association studies have identified the A-allele of rs1006737 within
CACNA1C as a risk factor for schizophrenia as well as mood disorders. Some evidence …
CACNA1C as a risk factor for schizophrenia as well as mood disorders. Some evidence …
Further evidence for genetic association of CACNA1C and schizophrenia: new risk loci in a Han Chinese population and a meta-analysis
Abstract CACNA1C (12p13. 3) has been implicated as a susceptibility gene for
schizophrenia by several replicated genome wide association studies. While these results …
schizophrenia by several replicated genome wide association studies. While these results …
An independent, replicable, functional and significant risk variant block at intron 3 of CACNA1C for schizophrenia
Z Wang, W Chen, Y Cao, Y Dou, Y Fu… - Australian & New …, 2022 - journals.sagepub.com
Objectives: Genome-wide association studies have identified a significant risk gene,
CACNA1C, for schizophrenia. In this study, we comprehensively investigated a large set of …
CACNA1C, for schizophrenia. In this study, we comprehensively investigated a large set of …