Research suggests overlap in brain regions undergoing neurodegeneration in Parkinson's
and Alzheimer's disease. To assess the clinical significance of this, we applied a validated …

Objective To assess regions and patterns of brain atrophy in patients with Parkinson disease
(PD) with normal cognition (PD-NC), mild cognitive impairment (PD-MCI), and dementia …

Background: Cognitive impairment is very common in patients with Parkinson's disease
(PD). Brain changes accompanying cognitive decline in PD are still not fully established …

We investigated the brain atrophy distribution pattern and rate of regional atrophy change in
Parkinson's disease (PD) in association with the cognitive status to identify the …

Mild cognitive impairment in Parkinson's disease is associated with progression to dementia
(Parkinson's disease dementia) in a majority of patients. Determining structural imaging …

Background Parkinson disease with dementia (PDD) results from neuropathological
changes in cortical and subcortical brain regions. Voxel-based morphometric analysis of …

Neuropsychological (mostly posterior-cortical) deficits, quantitative magnetic resonance
imaging (MRI) atrophy patterns, and low cerebrospinal fluid (CSF) levels of amyloid-β have …

Background Longitudinal neuroimaging studies could provide insights into pathophysiology
of cognitive impairment in PD. We examined the role of hippocampal atrophy and cerebral …

Objective Hippocampal atrophy has been associated with mild cognitive impairment (MCI) in
Parkinson's disease (PD). However, literature on how hippocampal atrophy affects the …

We studied eight clinically non-demented PD patients and ten age-matched controls with
serial volumetric T 1-weighted MRI. All PD patients underwent full neuropsychological …