Membrane-type 1 matrix metalloproteinase (MT1-MMP) is a zinc-dependent type-I
transmembrane metalloproteinase involved in pericellular proteolysis, migration and …

For over 20 years, membrane type 1 matrix metalloproteinase (MT1-MMP) has been
recognized as a key component in cancer progression. Initially, the primary roles assigned …

Matrix metalloproteinases (MMPs) are believed to play a pivotal role in malignant behavior
of cancer cells such as rapid tumor growth, invasion, and metastasis by degrading …

Degradation of extracellular matrix (ECM) is one of the first steps in tumor invasion and
metastasis. Matrix metalloproteinases (MMP) have been strongly implicated in this step …

Membrane type 1 matrix metalloproteinase (MT1-MMP/MMP14) is a zinc-dependent type I
transmembrane metalloproteinase playing pivotal roles in the regulation of pericellular …

Pericellular proteolysis is a hallmark of tumor cell metastasis. The membrane type (MT)-
matrix metalloproteinases (MMPs) constitute a distinctive group of membrane-bound MMPs …

Localization of membrane type I matrix metalloproteinase (MT1-MMP) to the leading edge is
thought to be a crucial step during cancer cell invasion. However, its mechanisms and …

Abstract Background Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) is a
multifunctional protease implicated in metastatic progression ostensibly due to its ability to …

Membrane type 1-matrix metalloproteinase (MT1-MMP) is an integral type I transmembrane
multidomain zinc-dependent endopeptidase involved in extracellular matrix remodelling in …

Membranetype 1 matrix metalloproteinase (MT1MMP), a powerful modulator of the
pericellular environment, promotes migration, invasion, and proliferation of cells. To perform …