Nerve growth factor (NGF) is a neurotrophic factor for basal forebrain cholinergic neurons
and may be of benefit in neurodegenerative diseases of humans. A method is described to …

The biological activities of recombinant human nerve growth factor (rhNGF) produced by
Chinese hamster ovary (CHO) cells that were transfected with human NGF gene were …

Nerve growth factor (NGF) is required for the differentiation and maintenance of sympathetic
and sensory neurons. In animal models, NGF prevents the death of septal and basal …

Nerve growth factor (NGF) supports sympathetic and sensory neurons in the peripheral
nervous system and also functions in the development and maintenance of cholinergic …

Biological and immunological properties of recombinant human, rat, and chicken nerve
growth factors (NGFs) were studied and compared. Recombinant NGF proteins were …

The human NGF gene was isolated and inserted downstream from murine leukemia virus
LTR in a plasmid having dihydrofolate reductase cDNA. The expression plasmid was …

A cDNA encoding a novel human neurotrophic factor (designated nerve growth factor2;
NGF2) was cloned from a human glioma cDNA library using a synthetic DNA …

Nerve growth factor (NGF) is a protein which plays a critical role in the development and
survival of not only peripheral neurons, but possibly also cholinergic brain neurons. The …

Of all isolated neurotrophic molecules Nerve Growth Factor (NGF) is the only one with a fully
established physiological function, at least in the peripheral nervous system (see Thoenen …

CONCLUSION NGF proteins probably act as informational molecules transferred from end
organs to the neurons of the sympathetic nervous system. The direct demonstration of the …