It has been known for a long time that schizophrenia and several related psychopathological
traits aggregate in families on a common genetic basis. Improved methodology of recent …

Although a decade has passed since the genetics of schizophrenia was examined for the
Schizophrenia Bulletin, the epigenetic puzzle of schizophrenia has not yielded its secrets to …

Genome-wide linkage studies, examining the relationship between the schizophrenia
syndrome (s) and possible susceptibility regions within the human genome have identified …

From the perspective of those of us working on the genetics of schizophrenia, recent
progress in identifying specific genetic risk factors at highly robust levels of statistical …

Abstract In the “Special Report on Schizophrenia” published in the Schizophrenia Bulletin in
1987, the genetic basis of schizophrenia was reviewed. Here, we provide our perspective on …

Archival family, twin and adoption studies have demonstrated that the lion's share of
susceptibility to manifest schizophrenia is determined by genetic factors. These same …

Twin, adoption and family studies have provided overwhelming but indirect evidence for a
significant genetic contribution to the etiology of schizophrenia. More recent studies …

Despite extensive genomic scans, linkage studies of multiplex pedigrees have been unable
to produce replicable evidence of genes predisposing to schizophrenia. This indicates that it …

Research in genetic epidemiology has provided powerful evidence that genetic factors
contribute to the familial transmission of schizophrenia. However, the precise mode of …

Schizophrenia is a genetic complex disease as it does not follow monogenic transmission
while non-familial environmental factors have a strong additional impact. A heterogeneous …