Mesenchymal stem cell licensing: enhancing MSC function as a translational approach for the treatment of tendon injury
DW Koch, LV Schnabel - American journal of veterinary …, 2023 - Am Vet Med Assoc
Tendon injuries are common in both veterinary and human clinical patients and result in
morbidity, pain, and lost athletic performance. Consequently, utilizing naturally occurring …
morbidity, pain, and lost athletic performance. Consequently, utilizing naturally occurring …
Use of mesenchymal stem cells for tendon healing in veterinary and human medicine: getting to the “core” of the problem through a one health approach
LV Schnabel, DW Koch - Journal of the American Veterinary …, 2023 - Am Vet Med Assoc
The purpose of this manuscript, which is part of the Currents in One Health series, is to take
a comparative approach to stem cell treatment for tendon injury and consider how the horse …
a comparative approach to stem cell treatment for tendon injury and consider how the horse …
Interleukin-1β in tendon injury enhances reparative gene and protein expression in mesenchymal stem cells
Tendon injury in the horse carries a high morbidity and monetary burden. Despite
appropriate therapy, reinjury is estimated to occur in 50–65% of cases. Although …
appropriate therapy, reinjury is estimated to occur in 50–65% of cases. Although …
Beneficial effects of autologous bone marrow-derived mesenchymal stem cells in naturally occurring tendinopathy
RKW Smith, NJ Werling, SG Dakin, R Alam… - PloS one, 2013 - journals.plos.org
Tendon injuries are a common age-related degenerative condition where current treatment
strategies fail to restore functionality and normal quality of life. This disease also occurs …
strategies fail to restore functionality and normal quality of life. This disease also occurs …
Therapeutics prior to mesenchymal stromal cell therapy improves outcome in equine orthopedic injuries
PN Bernardino, WA Smith, LD Galuppo… - American Journal of …, 2022 - Am Vet Med Assoc
OBJECTIVE Mesenchymal stromal (stem) cells (MSCs) have been studied to treat many
common orthopedic injuries in horses. However, there is limited information available on …
common orthopedic injuries in horses. However, there is limited information available on …
Mesenchymal stromal cells for treatment of tendon injuries: first insights from a controlled, randomized, blinded veterinary patient study
J Burk, L Wittenberg-Voges, W Brehm… - … Conference of the …, 2021 - elib.tiho-hannover.de
Tendon injuries represent a challenge in orthopedics due to limited regeneration and
frequentre-injuries. Treatment with multipotent mesenchymal stromal cells (MSC) is a …
frequentre-injuries. Treatment with multipotent mesenchymal stromal cells (MSC) is a …
Stem cells in veterinary medicine–attempts at regenerating equine tendon after injury
LE Richardson, J Dudhia, PD Clegg, R Smith - Trends in biotechnology, 2007 - cell.com
Stem cells have evoked considerable excitement in the animal-owning public because of
the promise that stem cell technology could deliver tissue regeneration for injuries for which …
the promise that stem cell technology could deliver tissue regeneration for injuries for which …
Mesenchymal stem cell therapy for equine tendinopathy
RKW Smith - Disability and rehabilitation, 2008 - Taylor & Francis
Optimal management of tendon overuse injuries in equine and human athletes should avoid
the formation of excessive scar tissue, regenerate normal tendon matrix, and reduce re …
the formation of excessive scar tissue, regenerate normal tendon matrix, and reduce re …
Mesenchymal stem cell therapy in equine musculoskeletal disease: scientific fact or clinical fiction?
SE Taylor, RK Smith, PD Clegg - Equine veterinary journal, 2007 - europepmc.org
The goal in the therapeutic use of mesenchymal stem cells (MSCs) in musculoskeletal
disease is to harness the regenerative nature of these cells focussing on their potential to …
disease is to harness the regenerative nature of these cells focussing on their potential to …
The lack of a representative tendinopathy model hampers fundamental mesenchymal stem cell research
M Meeremans, GR Van de Walle… - Frontiers in Cell and …, 2021 - frontiersin.org
Overuse tendon injuries are a major cause of musculoskeletal morbidity in both human and
equine athletes, due to the cumulative degenerative damage. These injuries present …
equine athletes, due to the cumulative degenerative damage. These injuries present …