The Gum–Gut axis: periodontitis and the risk of gastrointestinal cancers

G Baima, DG Ribaldone, F Romano, M Aimetti… - Cancers, 2023 - mdpi.com
Simple Summary Periodontitis, a chronic inflammatory disease of the gums, and the oral
microbiome have been recently implicated in the development of various cancers. Due to …

The oral-gut axis: periodontal diseases and gastrointestinal disorders

GA Lam, H Albarrak, CJ McColl… - Inflammatory bowel …, 2023 - academic.oup.com
One of the prospective sequelae of periodontal disease (PD), chronic inflammation of the
oral mucosa, is the development of inflammatory gastrointestinal (GI) disorders due to the …

[HTML][HTML] Exploring the oral-gut linkage: Interrelationship between oral and systemic diseases

K Yamazaki, N Kamada - Mucosal immunology, 2023 - Elsevier
The oral cavity harbors a diverse microbiota that plays a significant role in maintaining
homeostasis. Disruption of this balance can lead to various oral diseases, including …

The oral-gut axis: a missing piece in the IBD puzzle

S Kitamoto, N Kamada - Inflammation and Regeneration, 2023 - Springer
Inflammatory bowel disease (IBD) is a multifactorial intractable intestinal disease. Focusing
on only one facet of the pathogenesis of IBD is insufficient to fully capture the complexity of …

Periodontitis and Cancer: Beyond the boundaries of oral cavity

A Amato - Cancers, 2023 - mdpi.com
Oral squamous cell carcinoma (OSCC) is the 16th most common cancer and the 15th
leading cause of death worldwide, with an incidence of 4 cases per 100,000 people [1]. The …

[HTML][HTML] Oral-gut axis as a novel biological mechanism linking periodontal disease and systemic diseases: A review

K Yamazaki - Japanese Dental Science Review, 2023 - Elsevier
Substantial evidence suggests that periodontal disease increases the risk of developing and
progressing extraoral manifestations such as diabetes, atherosclerosis, rheumatoid arthritis …

Periodontal disease, tooth loss, and risk of oesophageal and gastric adenocarcinoma: a prospective study

CH Lo, S Kwon, L Wang, G Polychronidis, MD Knudsen… - Gut, 2021 - gut.bmj.com
We read with great interest the study by Coker et al 1 that provided supportive evidence for
the role of oral microbiota in gastric cancer. A few studies also highlighted the possible link …

Oral microbiome and oral and gastrointestinal cancer risk

J Ahn, CY Chen, RB Hayes - Cancer Causes & Control, 2012 - Springer
A growing body of evidence implicates human oral bacteria in the etiology of oral and
gastrointestinal cancers. Epidemiological studies consistently report increased risks of these …

The “Gum–Gut” axis in inflammatory bowel diseases: a hypothesis-driven review of associations and advances

KM Byrd, AS Gulati - Frontiers in immunology, 2021 - frontiersin.org
In modern medicine, the oral cavity has often been viewed as a passive conduit to the upper
airways and gastrointestinal tract; however, its connection to the rest of the body has been …

Periodontitis and progression of gastrointestinal cancer: current knowledge and future perspective

K Nasiri, M Amiri Moghaddam, EA Etajuri… - Clinical and …, 2023 - Springer
Periodontitis is a polymicrobial disorder caused by dysbiosis. Porphyromonas gingivalis (P.
gingivalis) and Fusobacterium nucleatum (F. nucleatum) are pathobiont related to …