Platelet function testing in atherothrombotic disease

E Lerkevang Grove, RF Storey… - Current pharmaceutical …, 2012 - ingentaconnect.com
Platelet function testing was introduced more than a century ago with the invention of
bleeding time; a test which has now been replaced by more accurate methods. Light …

Application of platelet function testing to the bedside

CD Williams, G Cherala… - Thrombosis and …, 2010 - thieme-connect.com
The ability to test platelet reactivity in clinical practice could help in making informed
decisions on both initiation and titration of anti-platelet drug therapies. However, many …

Platelet function testing: methods of assessment and clinical utility

D Mylotte, D Foley, D Kenny - Cardiovascular & Hematological …, 2011 - ingentaconnect.com
Platelets play a central role in the regulation of both thrombosis and haemostasis yet tests of
platelet function have, until recently, been exclusively used in the diagnosis and …

Platelet function testing and implications for clinical practice

JP Collet, G Montalescot - Journal of cardiovascular …, 2009 - journals.sagepub.com
Platelets are key mediators in the pathophysiology of atherothrombotic disease.
Inappropriate platelet activation can lead to thrombosis and ischemic events. Platelet …

Monitoring antiplatelet therapy with point-of-care platelet function assays: a review of the evidence

JW Van Werkum, CM Hackeng, JJJ Smit… - Future …, 2008 - Taylor & Francis
Multiple studies have demonstrated that subgroups of patients receiving combination
therapy with aspirin and clopidogrel fail to produce the anticipated antiplatelet effect, and …

Platelet function testing in contemporary clinical and interventional practice

F Franchi, F Rollini, JR Cho, E Ferrante… - … treatment options in …, 2014 - Springer
Opinion statement Dual antiplatelet therapy with a combination of aspirin and an inhibitor of
the ADP P2Y 12 receptor is the recommended treatment for patients with acute coronary …

Platelet function testing: state of the art

AM Zeidan, PA Kouides, MA Tara… - Expert Review of …, 2007 - Taylor & Francis
Platelet function testing has evolved from crude tests, such as the bleeding time, to tests that
permit a relatively sophisticated evaluation of platelet activity. Nonetheless, these tests are …

Platelet function testing: update and future directions

JB Larsen, AM Hvas, JA Hojbjerg - Seminars in Thrombosis …, 2023 - thieme-connect.com
Platelets play a key role in maintaining normal hemostasis and are also recognized as
partners in the development of arterial thrombosis. Today, platelet function testing is used for …

Platelet function testing and risk of bleeding complications

JL Ferreiro, D Sibbing… - Thrombosis and …, 2010 - thieme-connect.com
Antiplatelet therapy has a key role in preventing atherothrombotic events in patients with
coronary artery disease, particularly in those undergoing revascularisation procedures …

Clinical tests of platelet function

M Lordkipanidzé, AM Hvas, P Harrison - Platelets, 2019 - Elsevier
Traditionally, platelet function assays have been developed for the diagnosis and
management of patients presenting with bleeding problems rather than thrombosis …