Gut bacterial β-D-glucuronidases (GUSs) catalyze the removal of glucuronic acid from liver-
produced β-D-glucuronides. These reactions can have deleterious consequences when …

Abstract MSTG-A, MSTG-B and Gualtherin are three natural methyl salicylate glycosides
isolated from Dianbaizhu (Gaultheria leucocarpa var. yunnanensis), which is a traditional …

To understand that 18β-Glycyrrhetic acid 3-O-mono-β-D-glucuronide (GAMG) showed better
pharmacological activity and drug-like properties than 18β-Glycyrrhizin (GL); a rapid and …

Mycophenolate mofetil (MMF) is a viable therapeutic option against various immune
disorders as a chemotherapeutic agent. Nevertheless, its application has been undermined …

Herein, we scrutinized the inhibitory potential of five xanthones and a flavonoid, sourced
from Centaurium spicatum, against β-glucuronidase activity. The results showed that …

The direct inhibition of bacterial β-glucuronidase (βG) activity is expected to reduce the
reactivation of glucuronide-conjugated drugs in the intestine, thereby reducing drug toxicity …

Ulcerative colitis (UC) is an inflammatory bowel disease that is often resistant to current
treatment options, leading to a need for alternative therapies. Herbal products have shown …

Guavinoside B (GUB) is the main active substance in guava fruit and shows promising
biological activities. In this study, the inhibitory activity and mechanism of GUB on α …

ABSTRACT Glycyrrhetinic acid 3-O-mono-β-d-glucuronide (GAMG), which possesses a
higher sweetness and stronger pharmacological activity than those of glycyrrhizin (GL), can …

A yellow resin (gamboge) from Garcinia hanburyi has been widely used as folk medicine
due to its antibacterial and antitumor activities. We isolated four α-glucosidase inhibitory …