[HTML][HTML] α-Glucosidase and Bacterial β-Glucuronidase Inhibitors from the Stems of Schisandra sphaerandra Staph

G Rao, H Yu, M Zhang, Y Cheng, K Ran, J Wang… - Pharmaceuticals, 2022 - mdpi.com
α-Glucosidase (AGS) is a therapeutic target for Type 2 diabetes mellitus (T2DM) that tends to
complicate with other diseases. Some medications for the treatment of T2DM complications …

[HTML][HTML] Discovery and Characterization of the Key Constituents in Ginkgo biloba Leaf Extract With Potent Inhibitory Effects on Human UDP-Glucuronosyltransferase …

HL Pang, GH Zhu, QH Zhou, CZ Ai, YD Zhu… - Frontiers in …, 2022 - frontiersin.org
Human UDP-glucuronosyltransferase 1A1 (hUGT1A1) is one of the most essential phase II
enzymes in humans. Dysfunction or strong inhibition of hUGT1A1 may result in …

Identification of Potential α-Glucosidase Inhibitors from American Ginseng Processed Products by UHPLC-Q-Orbitrap/MS and Molecular Docking

L Liang, X Liu, J Shao, J Shen, Y Yao, X Huang, G Cai… - Food Biophysics, 2024 - Springer
The traditional herb American ginseng (Panax quinquefolium L.) can be processed into two
common products: dried American ginseng (DAG) and red American ginseng (RAG), which …

Polyphenolic rich extract of Oroxylum indicum alleviate β-glucuronidase activity via down-regulate oxidative stress: Experimental and computational studies

P Pathak, J Novak, V Naumovich, M Grishina… - Biocatalysis and …, 2020 - Elsevier
Oroxilum indicum has an extensive history in the Indian traditional medicine system. The
root and stem bark of this plant is well accepted for the treatment, prevention, and cure of …

α-Glucosidase inhibitors from brown rice bound phenolics extracts (BRBPE): Identification and mechanism

C Ye, R Zhang, L Dong, J Chi, F Huang, L Dong… - Food chemistry, 2022 - Elsevier
Brown rice bound phenolics extracts (BRBPE) have been reported to possess α-glucosidase
inhibitory effects, the specific enzyme inhibitors involved in this process were unknown …

Effect of saikosaponins and extracts of vinegar-baked Bupleuri Radix on the activity of β-glucuronidase

X Chen, T Yu, Z Chen, R Zhao, S Mao - Xenobiotica, 2014 - Taylor & Francis
In Traditional Chinese Medicine, liver targeting is usually achieved by coadministration with
Vinegar-baked Radix Bupleuri (VBRB), but the mechanism is unclear. In this paper, the …

[PDF][PDF] Effects of total glycosides of Qiwei Baizhu powder on intestinal microbiota and enzyme activities in diarrhea mice

G XIE, Y TANG, Y WU, L HUANG… - Biotechnology …, 2021 - biotech.aiijournal.com
To explore the material basis of Qiwei Baizhu Powder (QWBZP) in dysbacteria diarrhea
treatment, the total glycosides (TG) from QWBZP was extracted, and the effects of TG on the …

Purification and characterization of a novel β-glucuronidase precisely converts glycyrrhizin to glycyrrhetinic acid 3-O-mono-β-D-glucuronide from plant endophytic …

Q Zhang, B Gao, Y Xiao, H Yang, Y Wang, L Du… - International Journal of …, 2020 - Elsevier
Glycyrrhetinic acid monoglucuronide (GAMG) is an innovative functional sweetener with
higher sweetness and stronger pharmacological activity than glycyrrhizin (GL). A novel β …

[HTML][HTML] Ginseng berry prevents alcohol-induced liver damage by improving the anti-inflammatory system damage in mice and quality control of active compounds

DY Lee, MJ Kim, D Yoon, YS Lee, GS Kim… - International Journal of …, 2019 - mdpi.com
The ginseng berry contains a variety of biologically active compounds and has a higher
ginsenoside content than its roots. This study focused on the hepatoprotective activity of …

[HTML][HTML] α-Glucosidase inhibitors from Chinese bayberry (Morella rubra Sieb. et Zucc.) fruit: molecular docking and interaction mechanism of flavonols with different B …

Y Liu, L Zhan, C Xu, H Jiang, C Zhu, L Sun, C Sun… - RSC advances, 2020 - pubs.rsc.org
Inhibition of α-glucosidase alleviates postprandial high glycemic levels in diabetic or
prediabetic population. In Chinese bayberry fruit, myricetin, quercetin and kaempferol are …