Screening and structural characterization of potential α-glucosidase inhibitors from Radix Astragali flavonoids extract by ultrafiltration LC-DAD-ESI-MS n
W Jiang, H Kan, P Li, S Liu, Z Liu - Analytical Methods, 2015 - pubs.rsc.org
Inhibition of intestinal α-glucosidase activity is one important mechanism for the
management of diabetes mellitus (DM). Identifying plants with α-glucosidase inhibitory …
management of diabetes mellitus (DM). Identifying plants with α-glucosidase inhibitory …
Inhibitory effect of flavonoid glycosides on digestive enzymes: In silico, in vitro, and in vivo studies
Flavonoid glycosides (FGs) appear to be good candidates for controlling blood glucose
levels, so regular consumption of vegetables/fruits rich in FGs may prevent the …
levels, so regular consumption of vegetables/fruits rich in FGs may prevent the …
Rapid Screening for α-Glucosidase Inhibitors from Gymnema sylvestre by Affinity Ultrafiltration–HPLC-MS
G Chen, M Guo - Frontiers in pharmacology, 2017 - frontiersin.org
Gymnema sylvestre R. Br.(Asclepiadaceae) has been known to posses potential anti-
diabetic activity, and the gymnemic acids were reported as the main bioactive components …
diabetic activity, and the gymnemic acids were reported as the main bioactive components …
Inhibitory Effect of GE974 isolated from Gyrophora esculenta on
This study was conducted to search for the ${\alpha}-glucosidase $ inhibitor from the natural
products. In the previous study, the water extract of Gyrophora esculenta exhibited a potent …
products. In the previous study, the water extract of Gyrophora esculenta exhibited a potent …
2-Oxo-1, 2, 3, 4-tetrahydropyrimidines ethyl esters as potent β-glucuronidase inhibitors: one-pot synthesis, in vitro and in silico studies
Background: Glucuronidation is essential for the metabolism and excretion of toxic
substances. β-Glucuronidase enzyme slows down the process of glucuronidation, and thus …
substances. β-Glucuronidase enzyme slows down the process of glucuronidation, and thus …
Glycyrrhizin affects the pharmacokinetics of omeprazole in rats through inducing the activity of CYP3A4, CYP2C19, and P-gp
J Chen, G Li, Q Liu - Lat. Am. J. Pharm, 2018 - latamjpharm.org
Omeprazole and glycyrrhizin are widely used for the treatment of peptic ulcer in China clin-
ics. This study investigates the effects of glycyrrhizin on the pharmacokinetics of omeprazole …
ics. This study investigates the effects of glycyrrhizin on the pharmacokinetics of omeprazole …
Chemical Constituent of β-Glucuronidase Inhibitors from the Root of Neolitsea acuminatissima
CH Lin, HJ Chou, CC Chang, IS Chen, HS Chang… - Molecules, 2020 - mdpi.com
Neolitsea acuminatissima (Lauraceae) is an endemic plant in Taiwan. One new carboline
alkaloid, demethoxydaibucarboline A (1), two new eudesmanolide-type sesquiterpenes …
alkaloid, demethoxydaibucarboline A (1), two new eudesmanolide-type sesquiterpenes …
Synthesis of 2-Aminopyrimidine Derivatives and Their Evaluation as β-Glucuronidase Inhibitors: In Vitro and In Silico Studies
Currently the discovery and development of potent β-glucuronidase inhibitors is an active
area of research due to the observation that increased activity of this enzyme is associated …
area of research due to the observation that increased activity of this enzyme is associated …
[HTML][HTML] α-Glucosidase inhibitory activity-guided identification of compounds from Clerodendrum bungei steud by HPLC-ESI-QTOF-MS/MS
H Xiao-Long, WAN Dan, SHU Jun, F Liang-Zi… - Digital Chinese …, 2019 - Elsevier
Objective To identify the compounds with α-glucosidase inhibitory activity from
Clerodendrum bungei Steud (Chou Mu Dan, 臭牡丹) using HPLC-ESI-QTOF-MS/MS …
Clerodendrum bungei Steud (Chou Mu Dan, 臭牡丹) using HPLC-ESI-QTOF-MS/MS …
[HTML][HTML] Effect of Glycyrrhiza uralensis against ulcerative colitis through regulating the signaling pathway of FXR/P-gp
Q Lu, X Wu, W Han, W Zhang, Y Wang… - American journal of …, 2021 - ncbi.nlm.nih.gov
Objective: Ulcerative colitis (UC) is a moderate to severe inflammatory bowel disease, with a
characteristic inflammatory response. Chinese herbal medicine can play a role in UC …
characteristic inflammatory response. Chinese herbal medicine can play a role in UC …