[HTML][HTML] A narrative review of mechanisms of ferroptosis in cancer: new challenges and opportunities
M Jiang, R Hu, R Yu, Y Tang, J Li - Annals of Translational …, 2021 - ncbi.nlm.nih.gov
Objective This article reviews the specific mechanism of ferroptosis in cancer and introduces
in detail the opportunities and challenges of ferroptosis-based cancer therapy, aiming to …
in detail the opportunities and challenges of ferroptosis-based cancer therapy, aiming to …
Targeting Ferroptosis as an Advance Strategy in Cancer Therapy
TA Muluh, Q Fu, X Ai, C Wang, W Chen… - Antioxidants & Redox …, 2024 - liebertpub.com
Ferroptosis, triggered by the buildup of lipid peroxidation and reliance on iron, is crucial in
maintaining cellular balance. Research related to ferroptosis has surged due to its distinct …
maintaining cellular balance. Research related to ferroptosis has surged due to its distinct …
Pharmacological targeting of ferroptosis in cancer treatment
MR Valashedi, A Nikoo… - Current Cancer Drug …, 2022 - ingentaconnect.com
Ferroptosis is a non-apoptotic mode of Regulated Cell Death (RCD) driven by excessive
accumulation of toxic lipid peroxides and iron overload. Ferroptosis could be triggered by …
accumulation of toxic lipid peroxides and iron overload. Ferroptosis could be triggered by …
[HTML][HTML] Ferroptosis in cancer: From molecular mechanisms to therapeutic strategies
Q Zhou, Y Meng, D Li, L Yao, J Le, Y Liu… - … and Targeted Therapy, 2024 - nature.com
Ferroptosis is a non-apoptotic form of regulated cell death characterized by the lethal
accumulation of iron-dependent membrane-localized lipid peroxides. It acts as an innate …
accumulation of iron-dependent membrane-localized lipid peroxides. It acts as an innate …
[HTML][HTML] Ferroptosis and its multifaceted role in cancer: mechanisms and therapeutic approach
H Chen, C Wang, Z Liu, X He, W Tang, L He, Y Feng… - Antioxidants, 2022 - mdpi.com
Ferroptosis, a new type of non-apoptotic cell death modality, is different from other modes of
cell death and has been primarily found in tumor cells. Previous studies have reported that …
cell death and has been primarily found in tumor cells. Previous studies have reported that …
[HTML][HTML] Ferroptosis: the silver lining of cancer therapy
Z Tang, Z Huang, Y Huang, Y Chen… - Frontiers in Cell and …, 2021 - frontiersin.org
Regulatory cell death has been a major focus area of cancer therapy research to improve
conventional clinical cancer treatment (eg chemotherapy and radiotherapy). Ferroptosis, a …
conventional clinical cancer treatment (eg chemotherapy and radiotherapy). Ferroptosis, a …
[HTML][HTML] Ferroptosis as a novel form of regulated cell death: Implications in the pathogenesis, oncometabolism and treatment of human cancer
F Pu, F Chen, Z Zhang, D Shi, B Zhong, X Lv… - Genes & …, 2022 - Elsevier
The treatment of cancer mainly involves surgical excision supplemented by radiotherapy
and chemotherapy. Chemotherapy drugs act by interfering with tumor growth and inducing …
and chemotherapy. Chemotherapy drugs act by interfering with tumor growth and inducing …
Functional role of ferroptosis on cancers, activation and deactivation by various therapeutic candidates-an update
THP Nguyen, B Mahalakshmi… - Chemico-biological …, 2020 - Elsevier
Ferroptosis is recently identified form of regulated cell death which differs from previously
identified cell death in a way that it is driven by iron-dependent lipid peroxide accumulation …
identified cell death in a way that it is driven by iron-dependent lipid peroxide accumulation …
Cashing in on ferroptosis against tumor cells: Usher in the next chapter
Ferroptosis is a new type of non-apoptotic regulated cell death (RCD) driven by unrestricted
lethal lipid peroxidation, which is totally distinct from other forms of RCD in genetic and …
lethal lipid peroxidation, which is totally distinct from other forms of RCD in genetic and …
[HTML][HTML] Progress and setbacks in translating a decade of ferroptosis research into clinical practice
FA von Samson-Himmelstjerna, B Kolbrink, T Riebeling… - Cells, 2022 - mdpi.com
Ten years after its initial description, ferroptosis has emerged as the most intensely studied
entity among the non-apoptotic forms of regulated cell death. The molecular features of …
entity among the non-apoptotic forms of regulated cell death. The molecular features of …