Objective This article reviews the specific mechanism of ferroptosis in cancer and introduces
in detail the opportunities and challenges of ferroptosis-based cancer therapy, aiming to …

Ferroptosis, triggered by the buildup of lipid peroxidation and reliance on iron, is crucial in
maintaining cellular balance. Research related to ferroptosis has surged due to its distinct …

Ferroptosis is a non-apoptotic mode of Regulated Cell Death (RCD) driven by excessive
accumulation of toxic lipid peroxides and iron overload. Ferroptosis could be triggered by …

Ferroptosis is a non-apoptotic form of regulated cell death characterized by the lethal
accumulation of iron-dependent membrane-localized lipid peroxides. It acts as an innate …

Ferroptosis, a new type of non-apoptotic cell death modality, is different from other modes of
cell death and has been primarily found in tumor cells. Previous studies have reported that …

Regulatory cell death has been a major focus area of cancer therapy research to improve
conventional clinical cancer treatment (eg chemotherapy and radiotherapy). Ferroptosis, a …

The treatment of cancer mainly involves surgical excision supplemented by radiotherapy
and chemotherapy. Chemotherapy drugs act by interfering with tumor growth and inducing …

Ferroptosis is recently identified form of regulated cell death which differs from previously
identified cell death in a way that it is driven by iron-dependent lipid peroxide accumulation …

Ferroptosis is a new type of non-apoptotic regulated cell death (RCD) driven by unrestricted
lethal lipid peroxidation, which is totally distinct from other forms of RCD in genetic and …

Ten years after its initial description, ferroptosis has emerged as the most intensely studied
entity among the non-apoptotic forms of regulated cell death. The molecular features of …