Background Historically, the target in the schistosomiasis control has shifted from infection to
morbidity, then back to infection, but now as a public health problem, before moving on to …

Praziquantel became available for the treatment of schistosomiasis and other trematode-
inflicted diseases in the 1970s. It was revolutionary because it could be administered orally …

In 1975 the Special Programme for Schistosomiasis Control was introduced in Brazil with
the objective of controlling this parasitic disease in six northeastern states. The methodology …

The clinical manifestations of schistosomiasis pass by acute, sub acute and chronic stages
that mirror the immune response to infection. The later includes in succession innate, TH1 …

Remarkable achievements have been made in the control of schistosomiasis in China, with
chemotherapy playing a seminal role. From the early 1950s through the early 1980s …

Summary Praziquantel,(2-cyclohexylcarbonyl)-1, 2, 3, 6, 7, 11b-hexa-hydro-2H pyrazino [2,
1a] isoquinolin-4-one, belongs to a new series of antischistosomal compounds. The results …

Major progress in studying the biology of schistosomes had been achieved since the late
1960s with the successful laboratory cultivation of the parasite's life cycle stages in the …