In this commentary, we address current clinical practice of long-term antidepressant use in
older adults with depression, and recommend improvements. Compared with younger …

Objectives Antidepressant use has increased in older adults recently. This study examines
the trends of antidepressant prescribing by prescription status (continuing vs. new …

Objective: The authors investigated the clinical outcomes of commonly used antidepressants
among older adults who initiated first-time antidepressants for depression by analyzing the 1 …

Background Frail older adults are commonly prescribed antidepressants. Yet, there is little
evidence to determine the efficacy and safety of antidepressants to treat depression with …

Late-life depression is a serious illness accompanied by medical morbidity, cognitive
decline and risk of suicide. Antidepressant medications are a cornerstone of treatment for …

OBJECTIVES: To compare depressed older (≥ 65) and younger (25–64) adults with regard
to antidepressant treatment patterns and to assess factors associated with 180day …

Objective The upsurge in prevalence and long-term use of antidepressants among older
adults might have profound health implications beyond depressive symptom management …

Antidepressants have been shown to reduce the risk of depression recurrence in adults,
justifying prolonged antidepressant maintenance therapy for most if not all patients …

This paper updates our previous review of the evidence base for managing depression in
old age while focusing more specifically on the use of antidepressants. Overall, recent …

Objectives The study aimed to determine the prevalence of documented side effects and
drug–drug interactions in older adults using antidepressants and their implications for …