Brain nicotinic receptors were studied in the frontal cortex, temporal cortex, hippocampus
and caudate nucleus in patients with Parkinson's disease (PD), Alzheimer's disease (AD) …

The status of cholinergic receptors in dementia is related to the question of potential
cholinergic therapy. Whilst muscarinic receptor binding is generally reported to be normal or …

Impairment of cholinergic transmission and decreased numbers of nicotinic binding sites are
wellknown features accompanying the cognitive dysfunction seen in Alzheimer's disease …

Alzheimer's disease (AD) and Parkinson's disease (PD) and to a lesser extent progressive
supranuclear palsy are characterized by dysfunction of the cholinergic basal forebrain …

Muscarinic and nicotinic cholinergic receptor distribution was studied by dry-mount
autoradiography in brains obtained postmortem from patients with senile dementia of …

Nicotinic ligand binding studies have shown rather early that the cholinoceptive system is
affected in Alzheimer's disease (AD). Today, molecular histochemistry enables one to study …

Muscarinic and nicotinic binding sites were analysed in lymphocytes from patients with
Alzheimer's disease, Multi-infarct dementia, Parkinson's disease and age-matched controls …

The study of brain muscarinic receptors began more than a century ago, long before the
existence of muscarinic receptors was postulated and then demonstrated. However, the …

Neuronal nicotinic acetylcholine receptors labelled with tritiated agonists are reduced in the
cerebral cortex in Alzheimer's disease (AD), but to date it has not been demonstrated which …

The present investigation analyzes the cellular distribution of muscarinic and nicotinic
acetylcholine receptors in rat neocortex, by use of monoclonal antibodies raised against …