INTRODUCTION Strong genetic associations have been found for a number of psychiatric
disorders. However, understanding the underlying molecular mechanisms remains …

Strong psychologically stressful events are known to have a long-lasting impact on behavior.
The consolidation of such, largely adaptive, behavioral responses to stressful events …

Abstract γ-aminobutyric acid (GABA) inhibitory interneurons play a key role in efferent and
afferent control of principle neuron activity in the prefrontal cortex (PFC), thereby regulating …

Depression is a common psychiatric disorder and a leading cause of disability worldwide.
Here we conducted a genome-wide association study meta-analysis of six datasets …

Post-traumatic stress disorder (PTSD) is a highly disabling condition, increasingly
recognized as both a disorder of mental health and social burden, but also as an anxiety …

Progress in clinical and affective neuroscience is redefining psychiatric illness as
symptomatic expression of cellular/molecular dysfunctions in specific brain circuits. Post …

Background Psychiatric disorders are multigenic diseases with complex etiology that
contribute significantly to human morbidity and mortality. Although clinically distinct, several …

Posttraumatic stress disorder (PTSD) is a heterogeneous disorder that affects individuals
exposed to trauma (eg, combat, interpersonal violence, and natural disasters). Although its …

Psychiatric disorders such as schizophrenia (SCZ), bipolar disorder (BD), and major
depressive disorder (MDD) arise from complex interactions between genetic and …

A variety of cognitive disorders are worsened by stress exposure and involve dysfunction of
the newly evolved prefrontal cortex (PFC). Exposure to acute, uncontrollable stress …