Background Affective temperaments have been shown to impact on the clinical
manifestations and the course of bipolar disorder. We investigated their influence on clinical …

The constructs of atypical depression, bipolar II disorder and borderline personality disorder
(BPD) overlap. We explored the relationships between these constructs and their …

BackgroundIdentifying prodromal features that predate the onset of bipolar disorder (BD)
may enable the prevention of BD and aid early intervention. This review addresses two key …

Background: The modern concept of affective disorders focuses increasingly on the study of
subthreshold conditions on the border of manic or depressive episodes. Indeed, a spectrum …

This paper reviews recent evidence on two prevalent course patterns of major depressive
illness arising from dysthymic and cyclothymic temperamental substrates. The first pattern …

Bipolar disorder (BD) is a chronic, recurrent disorder carrying high morbidity and mortality,
leading to health costs of at least $45 billion per year (Kleinman et al., 2003). It is the sixth …

BACKGROUND:: Bipolar disorder comorbidity in obsessive–compulsive disorder (OCD) has
relevant implications on the symptomatological expression, complications and …

Background: Cycloid psychosis is a psychiatric disorder known for about 100 years. This
disorder is at present partly and simplified represented in the ICD-10. Sampling and …

Objective: To find, review, and critically evaluate evidence pertaining to the phenomenology
of pediatric bipolar disorder and its validity as a diagnosis. Methods: The present qualitative …

The concept of spectrum originally was used in physics to indicate an apparent qualitative
distinction arising from a quantitative continuum (ie, a series of colors formed when a beam …