Objectives To clarify the clinical features preceding the onset of bipolar disorder (BD) has
become a public health priority for the prevention of high morbidity and mortality. BD …

Affective temperament and psychopathological traits such as separation anxiety (SA) and
interpersonal sensitivity (IPS) are supposed to impact on the clinical manifestation and on …

Little longitudinal research has examined progression to more severe bipolar disorders in
individuals with “soft” bipolar spectrum conditions. We examine rates and predictors of …

Bipolar disorder (BD) is a complex and dynamic condition with a typical onset in late
adolescence or early adulthood followed by an episodic course with intervening periods of …

Objective: Prospective study designs ideally allow patients to be followed from the first
manifestations of the illness or even from an at-risk stage. It can thus provide data on the …

Based on available literature, this article reviews the challenges associated with diagnosing
pediatric bipolar disorder. The article also reviews and provides discussion on the …

INTRODUCTION: The cycloid psychoses have not been included in the modern
classifications—what makes scientific research difficult. The aim of the present study is to …

Although epidemiologic figures place the lifetime prevalence of bipolar disorders at about
1%, current evidence indicates that the spectrum of bipolar disorders may account for 3-6 …

A half-century ago, it was thought that children could not have a diagnosis of major
depressive disorder (MDD). With the acceptance of pediatric-onset MDD as a diagnosis, we …

Pediatric onset bipolar disorder (BD) is a challenging diagnosis with potentially debilitating
outcomes. This review aims to critically evaluate recently published literature relevant to the …