[HTML][HTML] A comprehensive review on celastrol, triptolide and triptonide: Insights on their pharmacological activity, toxicity, combination therapy, new dosage form and …

J Song, GN He, L Dai - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Celastrol, triptolide and triptonide are the most significant active ingredients of Tripterygium
wilfordii Hook F (TWHF). In 2007, the 'Cell'journal ranked celastrol, triptolide, artemisinin …

[HTML][HTML] Tripterygium hypoglaucum (Lévl.) Hutch and Its Main Bioactive Components: Recent Advances in Pharmacological Activity, Pharmacokinetics and Potential …

J Zhao, F Zhang, X Xiao, Z Wu, Q Hu, Y Jiang… - Frontiers in …, 2021 - frontiersin.org
Tripterygium hypoglaucum (Lévl.) Hutch (THH) is believed to play an important role in health
care and disease treatment according to traditional Chinese medicine. Moreover, it is also …

Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae)

AM Brinker, J Ma, PE Lipsky, I Raskin - Phytochemistry, 2007 - Elsevier
Plants in the genus Tripterygium, such as Tripterygium wilfordii Hook. f., have a long history
of use in traditional Chinese medicine. In recent years there has been considerable interest …

Triptolide: structural modifications, structure–activity relationships, bioactivities, clinical development and mechanisms

ZL Zhou, YX Yang, J Ding, YC Li, ZH Miao - Natural product reports, 2012 - pubs.rsc.org
Covering: 1972 to 2011 Triptolide, a principal bioactive ingredient of Tripterygium wilfordii
Hook F, has attracted extensive exploration due to its unique structure of a diterpenoid …

[HTML][HTML] Nanotechnology-based celastrol formulations and their therapeutic applications

PR Wagh, P Desai, S Prabhu, J Wang - Frontiers in Pharmacology, 2021 - frontiersin.org
Celastrol (also called tripterine) is a quinone methide triterpene isolated from the root extract
of Tripterygium wilfordii (thunder god vine in traditional Chinese medicine). Over the past …

The genus Tripterygium: A phytochemistry and pharmacological review

H Lv, L Jiang, M Zhu, Y Li, M Luo, P Jiang, S Tong… - Fitoterapia, 2019 - Elsevier
The genus Tripterygium belongs to the family Celastraceae, and contains three species, ie
Tripterygium wilfordii Hook. F, Tripterygium hypoglaucum (Levl.) Hutch. and Tripterygium …

[HTML][HTML] Triptolide: pharmacological spectrum, biosynthesis, chemical synthesis and derivatives

J Gao, Y Zhang, X Liu, X Wu, L Huang, W Gao - Theranostics, 2021 - ncbi.nlm.nih.gov
Triptolide, an abietane-type diterpenoid isolated from Tripterygium wilfordii Hook. F., has
significant pharmacological activity. Research results show that triptolide has obvious …

Triptolide: reflections on two decades of research and prospects for the future

L Tong, Q Zhao, E Datan, GQ Lin, I Minn… - Natural product …, 2021 - pubs.rsc.org
Covering: 2000 to 2020 Triptolide is a bioactive diterpene triepoxide isolated from
Tripterygium wilfordii Hook F, a traditional Chinese medicinal plant whose extracts have …

Triptolide: progress on research in pharmacodynamics and toxicology

XJ Li, ZZ Jiang, L Zhang - Journal of ethnopharmacology, 2014 - Elsevier
Abstract Ethnopharmacological relevance Tripterygium wilfordii Hook. f.(Tripterygium
wilfordii), also known as Huangteng and gelsemium elegan, is a traditional Chinese …

Celastrol: progresses in structure-modifications, structure-activity relationships, pharmacology and toxicology

W Hou, B Liu, H Xu - European journal of medicinal chemistry, 2020 - Elsevier
Celastrol, a principal bioactive ingredient of Tripterygium wilfordii Hook F, has gained
extensive exploration due to its unique structure features and multiple promising biological …